Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.66 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TET3 | O43151 | 1/20 | 0.48 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.48 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.48 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.48 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.48 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529201 | 0.90 | KMT2A (0.57) | OPRM1OPRL1KMT2ATET3FBXL19 | |
| SCHEMBL476404 | 0.81 | OPRM1 (1.00) | OPRM1OPRL1CHRM4OPRD1DRD2 | |
| Hydrochloric Acid SCHEMBL2473959 | 0.80 | OPRM1 (0.97) | OPRM1OPRL1CHRM4OPRD1DRD2 | |
| SCHEMBL27645407 | 0.78 | KMT2A (0.55) | OPRM1KMT2ATET3FBXL19CXXC5 | |
| SCHEMBL3406514 | 0.75 | OPRM1 (0.81) | OPRM1OPRL1CHRM4OPRD1DRD2 | |
| Hydrochloric Acid SCHEMBL8637817 | 0.74 | OPRM1 (0.79) | OPRM1OPRL1CHRM4OPRD1DRD2 | |
| SCHEMBL3895012 | 0.74 | OPRM1 (0.83) | OPRM1OPRL1CHRM4OPRD1DRD2 | |
| SCHEMBL13435360 | 0.74 | KCNA3 (0.59) | OPRM1KMT2ATET3FBXL19CXXC5 | |
| SCHEMBL373586 | 0.73 | OPRM1 (0.81) | OPRM1OPRL1KMT2ACHRM4OPRD1 | |
| SCHEMBL8350406 | 0.73 | OPRM1 (0.81) | OPRM1OPRL1CHRM4OPRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709029-A2 | METHODS FOR MAKING 4-TETRAZOLYL-4-PHENYLPIPERIDINE COMPOUNDS | EURO-CELTIQUE S.A. (LU) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005075455-A2 | METHODS FOR MAKING 4-TETRAZOLYL-4-PHENYLPIPERIDINE COMPOUNDS | EURO-CELTIQUE S.A. (LU) | 2005-08-18 | — | — | WO | disclosed |