Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.53 |
| ▸ | WNT3A | P56704 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017091 | 0.89 | HDAC6 (0.41) | HDAC6HTTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29729203 | 0.86 | HDAC6 (0.56) | HDAC6HTTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9178141 | 0.85 | LMNA (0.52) | HDAC6HTTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL31317898 | 0.85 | LMNA (0.52) | HDAC6HTTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL1965011 | 0.84 | KMT2A (0.65) | HDAC6HTTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL30447626 | 0.84 | KMT2A (0.65) | HDAC6HTTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL27799228 | 0.84 | ATM (0.51) | HDAC6HTTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6016892 | 0.83 | HTT (0.57) | HDAC6HTTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL31499307 | 0.83 | RAB9A (0.52) | HDAC6HTTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL31265619 | 0.81 | HDAC6 (0.52) | HDAC6HTTRAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |