Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482237 | 0.94 | TSHR (0.62) | ALDH1A1TSHRGPR35TP53MAPK1 | |
| SCHEMBL205380 | 0.79 | GPR35 (0.62) | ALDH1A1TSHRGPR35TP53MAPK1 | |
| SCHEMBL27725717 | 0.76 | MAPT (0.59) | ALDH1A1TSHRGPR35TP53MAPK1 | |
| SCHEMBL3030993 | 0.76 | LMNA (0.56) | ALDH1A1TSHRGPR35TP53MAPK1 | |
| 4-Nitrocatechol SCHEMBL1608536 | 0.76 | TSHR (0.69) | ALDH1A1TSHRGPR35TP53MAPK1 | |
| 4-Nitrocatechol SCHEMBL11765698 | 0.76 | TSHR (0.69) | ALDH1A1TSHRGPR35TP53MAPK1 | |
| 4-Nitrocatechol SCHEMBL156909 | 0.76 | TSHR (0.69) | ALDH1A1TSHRGPR35TP53MAPK1 | |
| SCHEMBL11796635 | 0.75 | GPR35 (0.53) | ALDH1A1TSHRGPR35TP53MAPK1 | |
| SCHEMBL840447 | 0.75 | HSD17B10 (0.67) | ALDH1A1TSHRTP53MAPK1SMN1; SMN2 | |
| SCHEMBL140502 | 0.75 | HSD17B10 (0.67) | ALDH1A1TSHRGPR35TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660080-A1 | FURANONE DERIVATIVES | Galileo Pharmaceuticals, Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016340-A1 | FURANONE DERIVATIVES | GALILEO PHARMACEUTICALS, INC. (US) | 2005-02-24 | — | — | WO | disclosed |