Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM5C | P41229 | 2/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017283 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL9736097 | 0.81 | KDM4C (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL1287025 | 0.78 | KDM5C (0.51) | ALDH1A1KMT2ASMN1; SMN2HSD17B10KDM5C | |
| SCHEMBL28431838 | 0.76 | KDM5C (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL28441622 | 0.75 | KDM4C (0.71) | ALDH1A1MEN1KMT2AKDM5CKDM4C | |
| SCHEMBL28431879 | 0.74 | KDM5C (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM5C | |
| SCHEMBL1287113 | 0.73 | NPC1 (0.45) | MEN1KMT2ASMN1; SMN2KDM5CKDM4C | |
| SCHEMBL28444103 | 0.72 | JMJD6 (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL28436634 | 0.72 | KDM5C (0.48) | ALDH1A1KDM5CKDM4CJMJD6 | |
| SCHEMBL1287029 | 0.72 | KDM4C (0.44) | SMN1; SMN2KDM5CKDM4CKDM4EKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060275217-A1 | Chemical exchange saturation transfer contrast agents | EPIX PHARMACEUTICALS, INC. | 2006-12-07 | — | — | US | disclosed |
| WO-2006121889-A2 | CHEMICAL EXCHANGE SATURATION TRANSFER CONTRAST AGENTS | EPIX PHARMACEUTICALS, INC. (US) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060275217-A1 | Chemical exchange saturation transfer contrast agents | SLC39A11, SLC30A7, SLC39A7 | ALDH1A1 4811/4885MEN1 558/4885KMT2A 850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.