Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163112 | 0.91 | — | — | |
| SCHEMBL2390035 | 0.88 | — | — | |
| SCHEMBL4394433 | 0.87 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL8467342 | 0.87 | — | — | |
| SCHEMBL6017579 | 0.87 | TSHR (0.42) | ALDH1A1TSHR | |
| SCHEMBL10379886 | 0.87 | ALDH1A1 (0.36) | ALDH1A1TSHRTHRB | |
| SCHEMBL1019318 | 0.85 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL6344570 | 0.84 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL11105491 | 0.84 | ALDH1A1 (0.43) | ALDH1A1TSHRTHRB | |
| SCHEMBL11819733 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110008284-A1 | NOVEL CLYCLOSPORIN ANALOGUES | ENANTA PHARMACEUTICALS, INC. | 2011-01-13 | — | — | US | claimed |
| US-20110008284-A1 | NOVEL CLYCLOSPORIN ANALOGUES | ENANTA PHARMACEUTICALS, INC. | 2011-01-13 | — | — | US | disclosed |
| EP-0601184-A1 | FUSED PYRIDAZINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110008284-A1 | NOVEL CLYCLOSPORIN ANALOGUES | CHP1, FKBP1B, FKBP1A | ALDH1A1 4167/4885TSHR 4866/4885THRB 4828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.