Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | GPR4 | P46093 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1623488 | 0.89 | AGTR2 (0.34) | AGTR2GPR4OPRK1PDE10A | |
| SCHEMBL1624183 | 0.89 | AGTR2 (0.35) | AGTR2GPR4 | |
| SCHEMBL28751555 | 0.80 | GPR4 (0.33) | AGTR2GPR4PDE10A | |
| SCHEMBL3947385 | 0.80 | GPR4 (0.43) | GPR4 | |
| SCHEMBL1625155 | 0.76 | PTGER4 (0.58) | — | |
| SCHEMBL27618331 | 0.76 | GPR4 (0.34) | GPR4 | |
| SCHEMBL27579860 | 0.76 | GPR4 (0.45) | GPR4 | |
| SCHEMBL27600077 | 0.75 | — | — | |
| SCHEMBL3949488 | 0.73 | AKT1 (0.35) | — | |
| SCHEMBL3947731 | 0.71 | GPR4 (0.34) | GPR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666480-A1 | Aryl or Heteroaryl Fused Imidazole Compounds as intermediates for Anti-Inflammatory And Analgesic Agents. | PFIZER PHARMACEUTICALS INC. (JP) | 2006-06-07 | — | — | EP | disclosed |