SCHEMBL6018337

SCHEMBL6018337

CON(C)c1nc(N)nc(N(OC)OC)n1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.38
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29231394 0.89 MAPT (0.33) RECQL
SCHEMBL197195 0.89 TP53 (0.43) TP53
SCHEMBL5936832 0.89 TP53 (0.43) TP53
SCHEMBL5247783 0.87 TP53 (0.38) TP53RECQL
SCHEMBL27955670 0.84 NPC1 (0.33) RECQL
SCHEMBL4063280 0.79 TP53 (0.48) TP53
SCHEMBL377579 0.77 ALDH1A1 (0.31)
SCHEMBL561793 0.76 LMNA (0.39)
SCHEMBL196708 0.75 TP53 (0.35) TP53
SCHEMBL11579222 0.75 MAPT (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100449054-C Aqueous liquid compositions of cyclodextrins or cyclodextrin derivatives and methods of using the same CIBA SC HOLDING AG (CH) 2009-01-07 CN claimed
CN-1813103-A Aqueous liquid compositions of cyclodextrine or cyclodextrine derivatives and a process using the said composition CIBA SC HOLDING AG (CH) 2006-08-02 CN claimed
US-20060138380-A1 Aqueous liquid compositions of cyclodextrine or cyclodextrine derivatives and a process using the said composition HUNTSMAN INTERNATIONAL LLC 2006-06-29 US claimed
CN-100449054-C Aqueous liquid compositions of cyclodextrins or cyclodextrin derivatives and methods of using the same CIBA SC HOLDING AG (CH) 2009-01-07 CN disclosed
CN-101044166-A Reactive polysaccharide derivates, their preparation and their use CIBA SC HOLDING AG (CH) 2007-09-26 CN disclosed
CN-1813103-A Aqueous liquid compositions of cyclodextrine or cyclodextrine derivatives and a process using the said composition CIBA SC HOLDING AG (CH) 2006-08-02 CN disclosed