SCHEMBL601835

SCHEMBL601835

Nc1cccnc1[N+](=O)[O-]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.50
ALDH1A1 P00352 6/20 0.46
MAPT P10636 5/20 0.46
HPGD P15428 1/20 0.46
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
PDE10A Q9Y233 1/20 0.43
POLB P06746 1/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
S1PR4 O95977 1/20 0.41
KDM4E B2RXH2 2/20 0.39
CTSB P07858 2/20 0.39
GAA P10253 1/20 0.39
IDO1 P14902 1/20 0.39
TDO2 P48775 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NCOA1 Q15788 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11901986 0.83 ALDH1A1 (0.45) HTTALDH1A1MAPTHPGDKMT2A
Hydrazine SCHEMBL28990400 0.78 PDE10A (0.55) ALDH1A1MAPTKMT2AMEN1PDE10A
Hydrazine SCHEMBL30355078 0.78 PDE10A (0.55) ALDH1A1MAPTKMT2AMEN1PDE10A
SCHEMBL294121 0.77 PDE10A (0.58) HTTALDH1A1MAPTKMT2AMEN1
SCHEMBL5643188 0.77 PDE10A (0.48) HTTALDH1A1MAPTKMT2AMEN1
SCHEMBL29579675 0.77 PDE10A (0.58) HTTALDH1A1MAPTKMT2AMEN1
SCHEMBL28984045 0.76 S1PR4 (0.39) HTTALDH1A1MAPTHPGDKMT2A
SCHEMBL8141010 0.75 HTT (0.37) HTTALDH1A1MAPTHPGDKMT2A
SCHEMBL799695 0.75 ALDH1A1 (0.51) HTTALDH1A1MAPTKMT2AMEN1
SCHEMBL251801 0.75 MAPT (0.45) ALDH1A1MAPTKMT2AMEN1PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120026327-A Acidic etching solution for aluminum-based circuit 深圳市溢诚电子科技有限公司 2025-05-23 CN claimed
CN-120006268-A Leadless high-phosphorus chemical nickel plating solution 珠海联鼎化工设备有限公司 2025-05-16 CN claimed
US-20240391874-A1 NOVEL, SAFE, ECONOMICAL AND AN EFFICIENT PROCESS FOR PREPARATION OF 3-FLUORO-2-NITRO PYRIDINE OF FORMULA I AASTRID LIFE SCIENCES PVT. LTD. (IN) 2024-11-28 US claimed
CN-117603134-A Nitration process for pyridine derivatives, process for preparing 2-nitro-3-aminopyridine and intermediates 上海凌凯医药科技有限公司 2024-02-27 CN claimed
EP-4251612-A1 NOVEL, SAFE, ECONOMICAL AND AN EFFICIENT PROCESS FOR PREPARATION OF 3-FLUORO-2-NITRO PYRIDINE OF FORMULA I Aastrid Life Sciences Pvt. Ltd. (IN) 2023-10-04 EP claimed
WO-2023119308-A1 NOVEL, SAFE, ECONOMICAL AND AN EFFICIENT PROCESS FOR PREPARATION OF 3-FLUORO-2-NITRO PYRIDINE OF FORMULA I AASTRID LIFE SCIENCES PVT. LTD. (IN) 2023-06-29 WO claimed
CN-107177588-A Modified glass bead carrier for fixing Azodrin degradation bacteria and preparation method thereof 光合强化(北京)生物科技有限公司 2017-09-19 CN claimed
US-7539006-B2 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2009-05-26 US claimed
CN-100456398-C Electrolyte for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORP (JP) 2009-01-28 CN claimed
US-20070029529-A1 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor KOMATSU AKIHIKO 2007-02-08 US claimed
US-5648496-A AMINATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-15 US claimed
CN-1138033-A Process for produducing aminonitropyridines SUMITOMO CHEMICAL CO (JP) 1996-12-18 CN claimed
EP-0735025-A1 Process for producing aminonitropyridines SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP claimed
EP-0188007-B1 PROCESS FOR THE PREPARATION OF 2-NITRO-3-AMINOPYRIDINE, AND THE N,N'-DI-(2-NITRO-3-PYRIDYL) UREA ITSELF OCCURRING AS AN INTERMEDIATE PRODUCT HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-19 EP claimed
US-4952697-A REACTING 3-AMINOPYRIDINE WITH PHOSGENE OR UREA, NITRATING AND HYDROLYSIS HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-28 US claimed
EP-0149537-B1 PROCESS FOR THE SYNTHESIS OF AMINONITROPYRIDINES ELI LILLY AND COMPANY (US) 1988-07-13 EP claimed
EP-0260613-A2 Imidazopyridine derivatives, their preparation and their use as PAF-antagonists G.D. Searle & Co. (US) 1988-03-23 EP claimed
EP-0188007-A2 Process for the preparation of 2-nitro-3-aminopyridine, and the N,N'-di-(2-nitro-3-pyridyl) urea itself occurring as an intermediate product HOECHST AKTIENGESELLSCHAFT (DE) 1986-07-23 EP claimed
US-4552967-A Process for the synthesis of intermediates in the preparation of diaminopyridines ELI LILLY AND COMPANY (US) 1985-11-12 US claimed
EP-0149537-A2 Process for the synthesis of aminonitropyridines ELI LILLY AND COMPANY (US) 1985-07-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391874-A1 NOVEL, SAFE, ECONOMICAL AND AN EFFICIENT PROCESS FOR PREPARATION OF 3-FLUORO-2-NITRO PYRIDINE OF FORMULA I AFF1, SCN1B, AFF2 HTT 3946/4885ALDH1A1 1077/4885MAPT 3357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.