Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561095 | 0.82 | MEN1 (0.42) | HTTNCF1ROCK1ALDH1A1TDP1 | |
| SCHEMBL8564386 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TDP1MAPTCYP3A4ALOX15 | |
| SCHEMBL8567050 | 0.80 | ROCK1 (0.34) | HTTNCF1ROCK1ALDH1A1TDP1 | |
| SCHEMBL28984045 | 0.80 | S1PR4 (0.39) | HTTNCF1ALDH1A1TDP1MAPT | |
| SCHEMBL18474451 | 0.80 | ALDH1A1 (0.39) | HTTROCK1ALDH1A1TDP1MAPT | |
| SCHEMBL8385465 | 0.80 | CYP3A4 (0.40) | HTTNCF1ROCK1ALDH1A1TDP1 | |
| SCHEMBL3218043 | 0.80 | NOS3 (0.50) | HTTALDH1A1TDP1MAPTCYP3A4 | |
| SCHEMBL3709618 | 0.80 | GAA (0.39) | HTTROCK1ALDH1A1TDP1MAPT | |
| SCHEMBL8565247 | 0.76 | ALDH1A1 (0.41) | HTTROCK1ALDH1A1TDP1MAPT | |
| SCHEMBL8562204 | 0.76 | S1PR4 (0.38) | ROCK1ALDH1A1MAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829812-B1 | Amplification of oligonucleotides containing non-standard nucleotides | NATIONAL SCIENCE FOUNDATION | 2020-11-10 | — | — | US | disclosed |
| US-6069277-A | Amination of electrophilic aromatic compounds by vicarious nucleophilic substitution | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| EP-0835237-A1 | AMINATION OF ELECTROPHILIC AROMATIC COMPOUNDS BY VICARIOUS NUCLEOPHILIC SUBSTITUTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-15 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| WO-1996035659-A1 | AMINATION OF ELECTROPHILIC AROMATIC COMPOUNDS BY VICARIOUS NUCLEOPHILIC SUBSTITUTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-11-14 | — | — | WO | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |
| US-5145482-A | Hair dye compositions based on 2,5-diamino-6-nitropyridine derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |
| US-4950302-A | Process for the production of 2,5-diamino-6-nitro-pyridine derivatives, their use in hair dye compositions and new 2,5-diamino-6-nitropyridine derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1990-08-21 | — | — | US | disclosed |