Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13841104 | 0.90 | KMT2A (0.62) | KDM4EGAAALDH1A1HPGDKMT2A | |
| SCHEMBL27451728 | 0.83 | KDM4E (0.54) | KDM4EGAAALDH1A1CASP1HSD17B10 | |
| SCHEMBL3657487 | 0.83 | ACHE (0.54) | KDM4EGAAALDH1A1CASP1HSD17B10 | |
| SCHEMBL1432838 | 0.81 | ALDH1A1 (0.50) | KDM4EGAAALDH1A1CASP1HSD17B10 | |
| SCHEMBL10891696 | 0.81 | KMT2A (0.57) | KDM4EGAAALDH1A1HSD17B10KMT2A | |
| SCHEMBL23417965 | 0.81 | KDM4E (0.52) | KDM4EGAAALDH1A1CASP1HSD17B10 | |
| SCHEMBL5085232 | 0.81 | MEN1 (0.57) | KDM4EGAAALDH1A1CASP1HSD17B10 | |
| SCHEMBL6947577 | 0.80 | BRD4 (0.67) | KDM4EGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL21464391 | 0.80 | KDM4E (0.61) | KDM4EGAAALDH1A1CASP1HSD17B10 | |
| SCHEMBL5084561 | 0.80 | GAA (0.51) | KDM4EGAAALDH1A1CASP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1683822-A1 | PREPOLYMER, PREPOLYMER COMPOSITION, HIGH MOLECULAR WEIGHT POLYMER HAVING STRUCTURE CONTAINING HOLE AND ELECTRICALLY INSULATING FILM | Daicel Chemical Industries, Ltd. (JP) | 2006-07-26 | — | — | EP | disclosed |