Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | PRKCA | P17252 | 3/20 | 0.59 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.59 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.57 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | DGKA | P23743 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2152312 | 1.00 | LMNA (0.64) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL2152798 | 1.00 | LMNA (0.64) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL2152823 | 1.00 | LMNA (0.64) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL2152572 | 1.00 | LMNA (0.64) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL2152579 | 1.00 | LMNA (0.64) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL2152561 | 1.00 | LMNA (0.64) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL18106999 | 1.00 | LMNA (0.64) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL3937050 | 0.95 | LMNA (0.70) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL10520413 | 0.94 | ALDH1A1 (0.57) | LMNAALDH1A1PRKCAPRKCEPRKCQ | |
| SCHEMBL9814037 | 0.94 | ALDH1A1 (0.57) | LMNAALDH1A1PRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154252-A1 | Methods and composition for identifying therapeutic agents of atherosclerotic plaque lesions | MARGUERIE GERARD | 2006-07-13 | — | — | US | disclosed |
| EP-1573067-A2 | METHODS FOR IDENTIFYING THERAPEUTIC AGENTS OF ATHEROSCLEROTIC PLAQUE LESIONS | Clinigenetics (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004057031-A2 | METHODS FOR IDENTIFYING THERAPEUTIC AGENTS OF ATHEROSCLEROTIC PLAQUE LESIONS | CLINIGENETICS (FR) | 2004-07-08 | — | — | WO | disclosed |