Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | RHOA | P61586 | 1/20 | 0.50 |
| ▸ | PTPRB | P23467 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | PTEN | P60484 | 1/20 | 0.50 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13972907 | 0.83 | SELP (0.52) | GAAMAPTALDH1A1FABP4 | |
| SCHEMBL30489981 | 0.83 | SELP (0.52) | GAAMAPTALDH1A1FABP4 | |
| SCHEMBL23845445 | 0.80 | NPC1 (0.44) | ITGB3ITGA2BGAAMAPTALDH1A1 | |
| SCHEMBL16299420 | 0.80 | FFAR1 (0.58) | FFAR1ITGB3ITGA2BSIRT1KEAP1 | |
| SCHEMBL12017476 | 0.80 | FFAR1 (0.58) | FFAR1ITGB3ITGA2BSIRT1KEAP1 | |
| SCHEMBL9489348 | 0.80 | FFAR1 (0.56) | FFAR1KEAP1FFAR4ALDH1A1 | |
| SCHEMBL31422531 | 0.80 | KEAP1 (0.59) | FFAR1ITGB3ITGA2BSIRT1KEAP1 | |
| SCHEMBL70271 | 0.78 | KEAP1 (0.74) | FFAR1KEAP1PTPRBCDC25ACDC25B | |
| SCHEMBL10388289 | 0.78 | GRIN2D (0.47) | GAAALDH1A1 | |
| SCHEMBL14401880 | 0.78 | ALDH1A1 (0.48) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141333-B1 | PROCESS FOR THE ENZYMATIC PREPARATION OF AMINO ACID DERIVATIVES WITH ENHANCED OPTICAL PURITY | DSM IP ASSETS BV (NL) | 2006-06-14 | — | — | EP | disclosed |
| EP-1013769-A1 | Process for the enzymatic preparation of amino acid derivatives with enhanced optical purity | DSM N.V. (NL) | 2000-06-28 | — | — | EP | disclosed |
| US-4404278-A | RADIOIMMUNOLOGY; FLUORESCENCE; ANTIBODIES | SYVA COMPANY (US) | 1983-09-13 | — | — | US | disclosed |
| EP-0052921-A1 | Methods and compositions for assaying for the production of 1,4-dihydropyridyl | SYVA COMPANY (US) | 1982-06-02 | — | — | EP | disclosed |