Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13222535 | 0.89 | SMN1; SMN2 (0.56) | FFAR1FFAR4NR1H4ALDH1A1 | |
| SCHEMBL8881437 | 0.84 | ALDH1A1 (0.53) | FFAR1FFAR4NR1H4ALDH1A1 | |
| SCHEMBL693471 | 0.81 | CA2 (0.52) | FFAR1NR1H4ALDH1A1CA2 | |
| SCHEMBL5652618 | 0.80 | FFAR1 (0.63) | FFAR1FFAR4KEAP1NR1H4ALDH1A1 | |
| SCHEMBL6018830 | 0.80 | FFAR1 (0.56) | FFAR1FFAR4KEAP1ALDH1A1 | |
| SCHEMBL69746 | 0.79 | FFAR1 (0.81) | FFAR1FFAR4KEAP1CA1CA2 | |
| SCHEMBL5914621 | 0.79 | CA2 (0.46) | ALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL25264643 | 0.77 | FFAR1 (0.77) | FFAR1FFAR4KEAP1CA1CA2 | |
| SCHEMBL8915282 | 0.77 | FFAR1 (0.60) | FFAR1FFAR4KEAP1NR1H4ALDH1A1 | |
| SCHEMBL7479986 | 0.77 | FFAR1 (0.60) | FFAR1FFAR4KEAP1NR1H4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238909-A | For preemergence or postemergence use | EASTMAN KODAK COMPANY (US) | 1993-08-24 | — | — | US | claimed |
| EP-0476760-A2 | 4-substituted isoxazole herbicides | EASTMAN KODAK COMPANY (US) | 1992-03-25 | — | — | EP | claimed |
| WO-2017192841-A1 | METHODS OF TREATMENT AND COMBINATION THERAPIES USING GCASE ACTIVATOR HETEROBICYCLIC AND RELATED COMPOUNDS | LYSOSOMAL THERAPEUTICS INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| US-5238909-A | For preemergence or postemergence use | EASTMAN KODAK COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0476760-A2 | 4-substituted isoxazole herbicides | EASTMAN KODAK COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |