Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | PRKX | P51817 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | MST1R | Q04912 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL601435 | 0.82 | NOTUM (0.33) | TDP1ALDH1A1 | |
| SCHEMBL16369379 | 0.82 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL28131229 | 0.81 | IRAK4 (0.37) | PLK4CHEK1AURKADAPK3MAP4K4 | |
| SCHEMBL16334638 | 0.81 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL28309799 | 0.79 | IRAK4 (0.36) | PLK4CHEK1AURKADAPK3MAP4K4 | |
| SCHEMBL19809947 | 0.78 | — | — | |
| SCHEMBL1218771 | 0.78 | TSHR (0.39) | MAP2K1TDP1ALDH1A1ATM | |
| SCHEMBL28210632 | 0.78 | NOS2 (0.33) | NNMTSIRT3TDP1NOS2IRAK4 | |
| SCHEMBL4115256 | 0.77 | GAA (0.37) | CHEK1RETPDGFRACDK5LRRK2 | |
| SCHEMBL19809939 | 0.77 | HMGCR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234444-A | Mixtures with insecticidal activity comprising sulfur-containing heterocyclylalkoxy compounds, oxides or salts thereof | 皮埃企业有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-115551352-A | Active compound combinations and fungicide compositions comprising them | 拜耳公司 | 2022-12-30 | — | — | CN | claimed |
| CN-112638894-B | Substituted thiophenecarboxamides and analogues as antibacterial agents | 拜耳公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-112601744-B | Substituted thiophenecarboxamides and analogues as antibacterial agents | 拜耳公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110475776-B | Tricyclic carboxamides for combating arthropods | 拜耳作物科学股份公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| CN-116406357-A | Modulators of MAS-related G protein receptor X2 and related products and methods | 伊赛恩特制药公司 | 2023-07-07 | — | — | CN | disclosed |
| EP-4192251-A1 | BIOINSECTICIDE | Kannar Earth Science, Ltd. (US) | 2023-06-14 | — | — | EP | disclosed |
| CN-116234444-A | Mixtures with insecticidal activity comprising sulfur-containing heterocyclylalkoxy compounds, oxides or salts thereof | 皮埃企业有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-115551352-A | Active compound combinations and fungicide compositions comprising them | 拜耳公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-101535274-A | Process for preparing difluoromethylpyrazolyl carboxylates | BASF SE (DE) | 2009-09-16 | — | — | CN | disclosed |
| EP-2086944-A1 | PROCESS FOR PREPARING DIFLUOROMETHYLPYRAZOLYL CARBOXYLATES | BASF SE (DE) | 2009-08-12 | — | — | EP | disclosed |
| CN-101506173-A | Process for preparing 3-dihalomethylpyrazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2009-08-12 | — | — | CN | disclosed |
| US-20090042725-A1 | Fungicidal Mixtures Based on 3,5-Disubstituted N-Biphenyl-Pyrazolcarboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2009-02-12 | — | — | US | disclosed |
| US-20090042724-A1 | Fungicidal mixtures based on 2,4-disubstituted n-biphenylpyrazolecarboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2009-02-12 | — | — | US | disclosed |
| WO-2008152138-A2 | METHOD FOR PRODUCING DIFLUOROMETHYL-SUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008145740-A1 | METHOD FOR THE PRODUCTION OF N-SUBSTITUTED (3-DIHALOMETHYL-1-METHYL-PYRAZOLE-4-YL) CARBOXAMIDES | BASF SE (DE) | 2008-12-04 | — | — | WO | disclosed |
| WO-2008053043-A1 | PROCESS FOR PREPARING DIFLUOROMETHYLPYRAZOLYL CARBOXYLATES | BASF SE (DE) | 2008-05-08 | — | — | WO | disclosed |
| US-5093347-A | Alleviating infections in diseased plants | MONSANTO COMPANY (US) | 1992-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042725-A1 | Fungicidal Mixtures Based on 3,5-Disubstituted N-Biphenyl-Pyrazolcarboxamides | CBR3, CBR1, STS | PLK4 3912/4885CHEK1 3114/4885AURKA 2961/4885 |
| US-20090042724-A1 | Fungicidal mixtures based on 2,4-disubstituted n-biphenylpyrazolecarboxamides | CBR3, CBR1, SNU13 | PLK4 4287/4885CHEK1 2632/4885AURKA 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.