Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GGT1 | P19440 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1867900 | 0.85 | NOTUM (0.31) | NOTUMALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL16369379 | 0.84 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL16334638 | 0.82 | ALDH1A1 (0.31) | ALDH1A1ALOX15 | |
| SCHEMBL601942 | 0.82 | PLK4 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL1864413 | 0.82 | ALDH1A1 (0.32) | NOTUMALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6231360 | 0.80 | HCAR3 (0.39) | NOTUMALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3298133 | 0.80 | NOTUM (0.33) | NOTUMALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19809947 | 0.79 | — | — | |
| SCHEMBL1218771 | 0.79 | TSHR (0.39) | ALDH1A1KDM4EHSD17B10TSHRTDP1 | |
| SCHEMBL4115256 | 0.78 | GAA (0.37) | ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775207-A | Morpholine-containing amide compound and preparation method and application thereof | 山东农业大学 | 2025-04-08 | — | — | CN | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| CN-114957123-B | 3- (difluoromethyl) -pyrazole-4-carboxylic ester derivative and preparation method and application thereof | 浙江工业大学 | 2023-11-28 | — | — | CN | claimed |
| CN-112119063-B | Method for producing 3-difluoromethylpyrazole compound, method for producing 3-difluoromethylpyrazole-4-carboxylic acid compound, and pyrazolidine compound | 富士胶片株式会社 | 2023-10-17 | — | — | CN | claimed |
| US-11149010-B2 | Producing method for 3-difluoromethylpyrazole compound, producing method for 3-difluoromethylpyrazole-4-carboxylic acid compound, and pyrazolidine compound | FUJIFILM CORPORATION (JP) | 2021-10-19 | — | — | US | claimed |
| US-20210061766-A1 | PRODUCING METHOD FOR 3-DIFLUOROMETHYLPYRAZOLE COMPOUND, PRODUCING METHOD FOR 3-DIFLUOROMETHYLPYRAZOLE-4-CARBOXYLIC ACID COMPOUND, AND PYRAZOLIDINE COMPOUND | FUJIFILM CORPORATION (JP) | 2021-03-04 | — | — | US | claimed |
| CN-112119063-A | Method for producing 3-difluoromethylpyrazole compound, method for producing 3-difluoromethylpyrazole-4-carboxylic acid compound, and pyrazolidine compound | 富士胶片株式会社 | 2020-12-22 | — | — | CN | claimed |
| CN-107501182-A | The trifluoromethyl of 1 substituted-phenyl 5（Difluoromethyl）4 pyrazole carboxylic acid synthetic methods | 中国农业大学 | 2017-12-22 | — | — | CN | claimed |
| CN-105418503-A | Synthesis method for 3-difluromethylation-1-methyl-1H-pyrazol-4-carboxylic acid ethyl ester | UNIV CHANGZHOU | 2016-03-23 | — | — | CN | claimed |
| CN-103570623-B | Preparation method of 3-(difluoromethyl)-1-methyl-1H-pyrazol-4-carboxylic acid | HUNAN RES INST CHEMICAL IND | 2015-05-20 | — | — | CN | claimed |
| CN-103570623-A | Preparation method of 3-(difluoromethyl)-1-methyl-1H-pyrazol-4-carboxylic acid | HUNAN RES INST CHEMICAL IND | 2014-02-12 | — | — | CN | claimed |
| CN-121449555-A | Preparation method of 3- (difluoromethyl) -1-methyl-pyrazole-4-formate and difluoro pyrazole acid | 江苏七洲绿色科技研究院有限公司 | 2026-02-03 | — | — | CN | disclosed |
| CN-119775207-A | Morpholine-containing amide compound and preparation method and application thereof | 山东农业大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-118852012-A | Synthesis method of high-yield difluoro pyrazole acid | 山东国邦药业有限公司 | 2024-10-29 | — | — | CN | disclosed |
| WO-2023237577-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS FOR USE IN THE TREATMENT OF HEART FAILURE WITH PRESERVED EJECTION FRACTION IN WOMEN | BAYER AKTIENGESELLSCHAFT (DE) | 2023-12-14 | — | — | WO | disclosed |
| EP-0217700-B1 | Benzimidazole derivatives, their preparation and their therapeutical use | SYNTHELABO (FR) | 1994-03-30 | — | — | EP | disclosed |
| CN-1078234-A | Pyrazole carboxanilide fungicide | MONSANTO CO (US) | 1993-11-10 | — | — | CN | disclosed |
| US-5223526-A | For plants | MONSANTO COMPANY (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993011117-A1 | PYRAZOLE CARBOXANILIDE FUNGICIDES | MONSANTO COMPANY (US) | 1993-06-10 | — | — | WO | disclosed |
| EP-0217700-A1 | Benzimidazole derivatives, their preparation and their therapeutical use | SYNTHELABO (FR) | 1987-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210061766-A1 | PRODUCING METHOD FOR 3-DIFLUOROMETHYLPYRAZOLE COMPOUND, PRODUCING METHOD FOR 3-DIFLUOROMETHYLPYRAZOLE-4-CARBOXYLIC ACID COMPOUND, AND PYRAZOLIDINE COMPOUND | CBR3, CYP2F1, DHPS | NOTUM 622/4885ALDH1A1 317/4885KDM4E 2987/4885 |
| US-11149010-B2 | Producing method for 3-difluoromethylpyrazole compound, producing method for 3-difluoromethylpyrazole-4-carboxylic acid compound, and pyrazolidine compound | CBR3, CYP2F1, DHPS | NOTUM 622/4885ALDH1A1 317/4885KDM4E 2987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.