Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574787 | 0.77 | MEN1 (0.33) | PKMALDH1A1ADRB2MAPTMEN1 | |
| SCHEMBL5116642 | 0.77 | GAA (0.43) | PKMALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL4664692 | 0.76 | GAA (0.33) | RAB9APKMALDH1A1ADRB2NPC1 | |
| SCHEMBL5666829 | 0.73 | ALDH1A1 (0.41) | RAB9ACYP1A2CYP2C19ALDH1A1NPC1 | |
| SCHEMBL16660490 | 0.66 | ADRB2 (0.51) | PKMCYP1A2CYP2C19ALDH1A1ADRB2 | |
| SCHEMBL4666506 | 0.66 | MAP4K1 (0.33) | ALDH1A1KDM4ESMN1; SMN2MAPTCASP1 | |
| SCHEMBL4737338 | 0.66 | KDM4E (0.36) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL4664846 | 0.59 | ALDH1A1 (0.33) | RAB9AALDH1A1NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL22245543 | 0.58 | MAPT (0.37) | RAB9ACYP1A2CYP2C19ALDH1A1NPC1 | |
| SCHEMBL24745609 | 0.57 | CA12 (0.41) | RAB9AALDH1A1NPC1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613626-A1 | CYCLIC BENZIMIDAZOLES | ALTANA Pharma AG (DE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004087701-A1 | CYCLIC BENZIMIDAZOLES | ALTANA PHARMA AG (DE) | 2004-10-14 | — | — | WO | disclosed |