Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 5/20 | 0.32 |
| ▸ | DRD3 | P35462 | 5/20 | 0.32 |
| ▸ | DRD4 | P21917 | 3/20 | 0.32 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | NR1D2 | Q14995 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139807 | 0.89 | DRD2 (0.38) | MAPK9MAPK10DRD2DRD3DRD4 | |
| SCHEMBL6022189 | 0.86 | CYP3A4 (0.36) | MAPK9MAPK10DRD2DRD3DRD4 | |
| SCHEMBL3480029 | 0.84 | MAPK9 (0.50) | MAPK9MAPK10DRD2DRD3DRD4 | |
| SCHEMBL7146894 | 0.84 | TMEM97 (0.40) | MAPK9MAPK10DRD2DRD3DRD4 | |
| SCHEMBL6021656 | 0.84 | DRD2 (0.39) | MAPK9MAPK10DRD2DRD3DRD4 | |
| SCHEMBL7142563 | 0.72 | TP53 (0.44) | LMNATP53ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7139566 | 0.72 | KDM4E (0.42) | MAPK9MAPK10GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL3479709 | 0.72 | MAPK9 (0.54) | MAPK9MAPK10DRD2DRD3DRD4 | |
| SCHEMBL3480006 | 0.71 | MAPK9 (0.55) | MAPK9MAPK10DRD2DRD3DRD4 | |
| SCHEMBL3480185 | 0.71 | MAPK9 (0.51) | MAPK9MAPK10DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663193-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES | Applied Research Systems ARS Holding N.V. (AN) | 2006-06-07 | — | — | EP | claimed |
| WO-2005025558-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES | APPLIED RESERACH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | claimed |