Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | NR1D2 | Q14995 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139807 | 0.91 | DRD2 (0.38) | HTTSMN1; SMN2LMNADRD2DRD3 | |
| SCHEMBL6021656 | 0.87 | DRD2 (0.39) | DRD2DRD3DRD4MAPK9MAPK10 | |
| SCHEMBL7146894 | 0.87 | TMEM97 (0.40) | DRD2DRD3DRD4MAPK9MAPK10 | |
| SCHEMBL6021776 | 0.86 | MAPK9 (0.33) | SMN1; SMN2LMNADRD2DRD3DRD4 | |
| SCHEMBL3480185 | 0.84 | MAPK9 (0.51) | CYP3A4MAPK14SMN1; SMN2LMNADRD2 | |
| SCHEMBL3479946 | 0.78 | MAPK9 (0.51) | SMN1; SMN2LMNAMAPK9MAPK10TRPV1 | |
| SCHEMBL3479709 | 0.77 | MAPK9 (0.54) | LMNADRD2DRD3DRD4MAPK9 | |
| SCHEMBL7142563 | 0.75 | TP53 (0.44) | SMN1; SMN2LMNA | |
| SCHEMBL7139566 | 0.75 | KDM4E (0.42) | HTTSMN1; SMN2MAPK9MAPK10 | |
| SCHEMBL6021494 | 0.73 | ACKR3 (0.38) | SMN1; SMN2LMNAACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663193-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES | Applied Research Systems ARS Holding N.V. (AN) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005025558-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES | APPLIED RESERACH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | disclosed |