Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262974 | 0.86 | CYP4F2 (0.55) | CYP4F2CYP4A11MEN1ALDH1A1KMT2A | |
| SCHEMBL28386822 | 0.83 | LMNA (0.38) | CYP4F2CYP4A11LMNAHSD17B10 | |
| SCHEMBL4658767 | 0.82 | LMNA (0.40) | CYP4F2CYP4A11MEN1ALDH1A1CYP1A2 | |
| SCHEMBL2036937 | 0.81 | ALOX15 (0.36) | CYP4F2CYP4A11MEN1ALDH1A1CYP1A2 | |
| SCHEMBL21815206 | 0.81 | CYP4F2 (0.34) | CYP4F2CYP4A11 | |
| SCHEMBL27313849 | 0.79 | — | — | |
| SCHEMBL16163571 | 0.79 | CYP4F2 (0.33) | CYP4F2CYP4A11LMNA | |
| SCHEMBL7511555 | 0.79 | CYP4F2 (0.33) | CYP4F2CYP4A11LMNA | |
| SCHEMBL11680514 | 0.79 | CYP4F2 (0.31) | CYP4F2CYP4A11 | |
| SCHEMBL6286232 | 0.78 | FDPS (0.40) | CYP4F2CYP4A11MEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668004-A1 | BENZOXAZOLE ACETONITRILES | Applied Research Systems ARS Holding N.V. (AN) | 2006-06-14 | — | — | EP | claimed |
| WO-2005026159-A1 | BENZOXAZOLE ACETONITRILES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | claimed |