Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023752 | 0.91 | SMN1; SMN2 (0.56) | TP53LMNAMAPTPKMSMN1; SMN2 | |
| SCHEMBL6022292 | 0.90 | SLC22A12 (0.55) | TP53LMNAMAPTPKMPOLB | |
| SCHEMBL5760368 | 0.90 | LMNA (0.50) | TP53LMNAMAPTPKMALDH1A1 | |
| SCHEMBL6022537 | 0.89 | PKM (0.51) | TP53LMNAMAPTPKMALDH1A1 | |
| SCHEMBL6022414 | 0.88 | PKM (0.49) | TP53LMNAMAPTPKMPOLB | |
| SCHEMBL6023208 | 0.86 | PKM (0.60) | TP53LMNAMAPTPKMALDH1A1 | |
| SCHEMBL6022363 | 0.85 | FFAR1 (0.55) | TP53MAPTPKMSMN1; SMN2POLB | |
| SCHEMBL6023623 | 0.85 | PKM (0.70) | MAPTPKMPOLBGAABRAF | |
| SCHEMBL6022456 | 0.85 | PKM (0.51) | TP53LMNAMAPTPKMSMN1; SMN2 | |
| SCHEMBL6022442 | 0.84 | PKM (0.54) | TP53LMNAPKMSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009052-B2 | Sulfonamide derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-03-07 | — | — | US | disclosed |