Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | AR | P10275 | 9/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6022246 | 0.91 | TP53 (0.58) | SMN1; SMN2LMNATP53MAPTPOLB | |
| SCHEMBL5760654 | 0.89 | LMNA (0.48) | SMN1; SMN2LMNATP53MAPTPOLB | |
| SCHEMBL6022360 | 0.84 | POLB (0.53) | TP53MAPTPOLBPKMAR | |
| SCHEMBL6023759 | 0.84 | POLB (0.65) | MAPTPOLBPKMARGAA | |
| SCHEMBL6023780 | 0.83 | MAPT (0.59) | SMN1; SMN2LMNATP53MAPTGAA | |
| SCHEMBL6022243 | 0.83 | AR (0.61) | LMNATP53MAPTPOLBPKM | |
| SCHEMBL6023175 | 0.83 | KMT2A (0.52) | SMN1; SMN2POLBPKMGAATHRB | |
| SCHEMBL6023623 | 0.83 | PKM (0.70) | MAPTPOLBPKMARGAA | |
| SCHEMBL6022292 | 0.82 | SLC22A12 (0.55) | LMNATP53MAPTPOLBPKM | |
| SCHEMBL6022537 | 0.82 | PKM (0.51) | SMN1; SMN2LMNATP53MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009052-B2 | Sulfonamide derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-03-07 | — | — | US | disclosed |