Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12480601 | 0.87 | IRAK4 (0.40) | MCL1ELANETFPI2RAB9ANOTUM | |
| SCHEMBL16792773 | 0.84 | ALDH1A1 (0.45) | TUBB1MCL1NTSR1HTR2AHTR2C | |
| SCHEMBL265019 | 0.83 | PIK3CA (0.46) | TUBB1MCL1NTSR1HTR2AHTR2C | |
| SCHEMBL4175475 | 0.82 | TFPI2 (0.48) | TUBB1HTR2AHTR2CFABP4TFPI2 | |
| SCHEMBL12749675 | 0.81 | NOTUM (0.58) | TUBB1MCL1NTSR1HTR2AHTR2C | |
| SCHEMBL31607288 | 0.81 | NOTUM (0.58) | TUBB1MCL1NTSR1HTR2AHTR2C | |
| SCHEMBL7988808 | 0.81 | TUBB1 (0.60) | TUBB1HTR2CFABP4TFPI2HPGD | |
| SCHEMBL617201 | 0.81 | PRKCI (0.50) | TUBB1NTSR1TFPI2NOTUMLPO | |
| SCHEMBL29082806 | 0.80 | FABP4 (0.42) | TUBB1MCL1NTSR1HTR2AHTR2C | |
| SCHEMBL14720210 | 0.80 | NTSR1 (0.46) | TUBB1MCL1NTSR1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017095054-A1 | COMPOUND FOR ORGANIC-ELECTRIC ELEMENT, ORGANIC-ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE FOR SAME | 덕산네오룩스 주식회사 | 2017-06-08 | — | — | WO | disclosed |
| EP-1611097-A1 | INDOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DESEASES | Pfizer Limited (GB) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004080964-A1 | INDOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DISEASES | PFIZER LIMITED (GB) | 2004-09-23 | — | — | WO | disclosed |