Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 16/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5762495 | 0.91 | POLB (0.44) | POLBARTP53MAPTLMNA | |
| SCHEMBL6022249 | 0.90 | POLB (0.46) | POLBAR | |
| SCHEMBL6022518 | 0.85 | POLB (0.45) | POLBARTP53MAPTLMNA | |
| SCHEMBL6022377 | 0.84 | POLB (0.47) | POLBARLMNA | |
| SCHEMBL6022373 | 0.84 | POLB (0.56) | POLBARTP53MAPTLMNA | |
| SCHEMBL6022237 | 0.83 | POLB (0.55) | POLBAR | |
| SCHEMBL6022288 | 0.82 | POLB (0.50) | POLBARTP53MAPTLMNA | |
| SCHEMBL6022359 | 0.82 | POLB (0.51) | POLBAR | |
| SCHEMBL6022564 | 0.82 | PKM (0.49) | POLBARLMNA | |
| SCHEMBL5759507 | 0.82 | POLB (0.42) | POLBAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009052-B2 | Sulfonamide derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-03-07 | — | — | US | claimed |
| US-20050004367-A1 | Sulfonamide derivatives | DU DANIEL Y (US) | 2005-01-06 | — | — | US | claimed |
| US-7009052-B2 | Sulfonamide derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-03-07 | — | — | US | disclosed |
| US-20050004367-A1 | Sulfonamide derivatives | DU DANIEL Y (US) | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004367-A1 | Sulfonamide derivatives | AR, SULT2A1, SHBG | POLB 4297/4885AR 1/4885TP53 2291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.