Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6022242 | 0.87 | ALDH1A1 (0.60) | ARPKMGAAPOLBMEN1 | |
| SCHEMBL6023759 | 0.85 | POLB (0.65) | ARPKMGAAPOLBMEN1 | |
| SCHEMBL6022354 | 0.84 | AR (0.49) | ARPKMGAAPOLBMEN1 | |
| SCHEMBL6022243 | 0.84 | AR (0.61) | ARPKMGAAPOLBMEN1 | |
| SCHEMBL6023623 | 0.83 | PKM (0.70) | ARPKMGAAPOLBMAPT | |
| SCHEMBL5761367 | 0.83 | SIRT2 (0.44) | ARPKMGAA | |
| SCHEMBL6022358 | 0.82 | PKM (0.51) | ARPKMGAAPOLBALDH1A1 | |
| SCHEMBL6022578 | 0.81 | AR (0.52) | ARPKMGAAPOLBMAPT | |
| SCHEMBL6023096 | 0.81 | MAPT (0.62) | ARPKMGAAPOLBMAPT | |
| SCHEMBL5759800 | 0.80 | HTT (0.50) | ARPKMGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009052-B2 | Sulfonamide derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-03-07 | — | — | US | disclosed |