Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 14/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6022442 | 0.90 | PKM (0.54) | PKMSIRT2SIRT6ARGAA | |
| SCHEMBL6022363 | 0.85 | FFAR1 (0.55) | PKMARGAAPOLB | |
| SCHEMBL6023623 | 0.85 | PKM (0.70) | PKMARGAAPOLB | |
| SCHEMBL6023208 | 0.84 | PKM (0.60) | PKMARGAAPOLBALDH1A1 | |
| SCHEMBL5761786 | 0.84 | PKM (0.52) | PKMSIRT2SIRT6ARPOLB | |
| SCHEMBL5761367 | 0.84 | SIRT2 (0.44) | PKMIKBKBSIRT2SIRT6AR | |
| SCHEMBL6022456 | 0.83 | PKM (0.51) | PKMSIRT2SIRT6ARGAA | |
| SCHEMBL6022340 | 0.82 | SLC22A12 (0.56) | PKMARGAAPOLB | |
| SCHEMBL6023071 | 0.82 | AR (0.53) | PKMARGAAPOLBALDH1A1 | |
| SCHEMBL6023482 | 0.82 | PKM (0.52) | PKMARGAAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7009052-B2 | Sulfonamide derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-03-07 | — | — | US | disclosed |