Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 13/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.45 |
| ▸ | PDE4A | P27815 | 10/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024770 | 0.83 | BMP1 (0.44) | BMP1 | |
| SCHEMBL6024495 | 0.83 | PDE4D (0.49) | PDE4DPDE4BPDE4APDE4CBMP1 | |
| SCHEMBL6023843 | 0.74 | BMP1 (0.44) | BMP1 | |
| SCHEMBL6025328 | 0.74 | HPGD (0.42) | BMP1 | |
| SCHEMBL6023388 | 0.73 | BMP1 (0.44) | BMP1 | |
| SCHEMBL6586929 | 0.72 | PDE4B (0.60) | PDE4DPDE4BPDE4APDE4CMAPK14 | |
| SCHEMBL6587335 | 0.71 | PDE4B (0.80) | PDE4DPDE4BPDE4APDE4CMAPK14 | |
| SCHEMBL6024907 | 0.71 | HDAC3 (0.39) | BMP1 | |
| SCHEMBL6024803 | 0.71 | OPRM1 (0.37) | BMP1 | |
| SCHEMBL6024200 | 0.70 | CYP3A4 (0.41) | PDE4DPDE4BPDE4APDE4CBMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363873-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1363873-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002070541-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITH KLINE BEECHAM CORPORATION (US) | 2002-09-12 | — | — | WO | disclosed |