SCHEMBL6024312

SCHEMBL6024312

CCCCCC(CN(O)C=O)C(=O)N(N)C(=O)OC(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 6/20 0.37
PDF Q9HBH1 2/20 0.37
MMP12 P39900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6023663 1.00 BMP1 (0.37) BMP1PDFMMP12
SCHEMBL6023680 0.83 PDF (0.38) BMP1PDFMMP12
SCHEMBL6023686 0.82 BMP1 (0.38) BMP1PDFMMP12
SCHEMBL6025846 0.80 BMP1 (0.37) BMP1PDF
SCHEMBL4960328 0.78 BMP1 (0.42) BMP1PDFMMP12
SCHEMBL4962086 0.78 BMP1 (0.41) BMP1PDFMMP12
SCHEMBL6024335 0.78 PDF (0.37) BMP1PDFMMP12
SCHEMBL4960824 0.77 BMP1 (0.42) BMP1PDFMMP12
SCHEMBL5006981 0.77 BMP1 (0.42) BMP1PDFMMP12
SCHEMBL4959841 0.77 BMP1 (0.42) BMP1PDFMMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363873-A4 PEPTIDE DEFORMYLASE INHIBITORS SMITHKLINE BEECHAM CORP (US) 2006-01-04 EP claimed
EP-1363873-A2 PEPTIDE DEFORMYLASE INHIBITORS SmithKline Beecham Corporation (US) 2003-11-26 EP claimed
WO-2002070541-A2 PEPTIDE DEFORMYLASE INHIBITORS SMITH KLINE BEECHAM CORPORATION (US) 2002-09-12 WO claimed