SCHEMBL6023680

SCHEMBL6023680

CCCCCC(CN(O)C=O)C(=O)N(NC)C(=O)OC(C)(C)C

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDF Q9HBH1 3/20 0.38
BMP1 P13497 6/20 0.38
MMP12 P39900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6023686 0.89 BMP1 (0.38) PDFBMP1MMP12
SCHEMBL6024335 0.85 PDF (0.37) PDFBMP1MMP12
SCHEMBL6024312 0.83 BMP1 (0.37) PDFBMP1MMP12
SCHEMBL6023663 0.83 BMP1 (0.37) PDFBMP1MMP12
SCHEMBL6024775 0.81 BMP1 (0.47) BMP1MMP12
SCHEMBL6023685 0.81 BMP1 (0.35) PDFBMP1MMP12
SCHEMBL4960328 0.81 BMP1 (0.42) PDFBMP1MMP12
SCHEMBL4962086 0.81 BMP1 (0.41) PDFBMP1MMP12
SCHEMBL4959841 0.80 BMP1 (0.42) PDFBMP1MMP12
SCHEMBL4960824 0.80 BMP1 (0.42) PDFBMP1MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363873-A4 PEPTIDE DEFORMYLASE INHIBITORS SMITHKLINE BEECHAM CORP (US) 2006-01-04 EP disclosed
EP-1363873-A2 PEPTIDE DEFORMYLASE INHIBITORS SmithKline Beecham Corporation (US) 2003-11-26 EP disclosed
WO-2002070541-A2 PEPTIDE DEFORMYLASE INHIBITORS SMITH KLINE BEECHAM CORPORATION (US) 2002-09-12 WO disclosed