Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19639848 | 1.00 | SIGMAR1 (0.73) | SIGMAR1MEN1KMT2AADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL9156272 | 0.98 | SIGMAR1 (0.71) | SIGMAR1MEN1KMT2A | |
| SCHEMBL8977010 | 0.89 | SIGMAR1 (0.65) | SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9249699 | 0.89 | SIGMAR1 (0.67) | SIGMAR1MEN1KMT2A | |
| SCHEMBL9156241 | 0.88 | SIGMAR1 (0.68) | SIGMAR1MEN1KMT2AADRB2ADRB1 | |
| SCHEMBL8976808 | 0.87 | SIGMAR1 (0.65) | SIGMAR1MEN1KMT2ASLC6A4 | |
| SCHEMBL8091277 | 0.86 | SIGMAR1 (0.91) | SIGMAR1MEN1KMT2A | |
| SCHEMBL9373855 | 0.85 | SIGMAR1 (1.00) | SIGMAR1MEN1KMT2A | |
| SCHEMBL9158626 | 0.85 | SIGMAR1 (0.73) | SIGMAR1MEN1KMT2ACNR1 | |
| SCHEMBL13359251 | 0.84 | SIGMAR1 (0.61) | SIGMAR1MEN1KMT2AADRB1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107205966-B | Arylalkyl amine compounds for preventing or treating cancer | 森梅威思大学 | 2021-01-26 | — | — | CN | claimed |
| EP-3226851-B1 | ARYLALKYLAMINE COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF CANCER | SEMMELWEIS UNIV (HU) | 2020-03-18 | — | — | EP | claimed |
| US-10258598-B2 | Compounds for use in the prevention or treatment of cancer | SEMMELWEIS UNIVERSITY (HU) | 2019-04-16 | — | — | US | claimed |
| US-20170340582-A1 | COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF CANCER | FUJIMOTO CO. LTD. (JP) | 2017-11-30 | — | — | US | claimed |
| EP-0284621-B1 | NEW PSYCHOSTIMULANT AGENT | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1995-01-18 | — | — | EP | claimed |
| EP-0617615-A1 | PHARMACEUTICAL COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1994-10-05 | — | — | EP | claimed |
| WO-1993012775-A1 | PHARMACEUTICAL COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-07-08 | — | — | WO | claimed |
| US-5220068-A | N-propyl-1-phenyl-2-alkylamines | CHINOIN GYOGYSZER - ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1993-06-15 | — | — | US | claimed |
| US-5075338-A | Using aryl secondary amine | CHINOIN GYOGYSZER- ES VERGYESZETI TERMEKEK GYARA RT. (HU) | 1991-12-24 | — | — | US | claimed |
| EP-0284621-A1 | NEW PSYCHOSTIMULANT AGENT. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1988-10-05 | — | — | EP | claimed |
| WO-1988002254-A1 | NEW PSYCHOSTIMULANT AGENT | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1988-04-07 | — | — | WO | claimed |
| CN-107205966-B | Arylalkyl amine compounds for preventing or treating cancer | 森梅威思大学 | 2021-01-26 | — | — | CN | disclosed |
| EP-3226851-B1 | ARYLALKYLAMINE COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF CANCER | SEMMELWEIS UNIV (HU) | 2020-03-18 | — | — | EP | disclosed |
| EP-3226852-B1 | ARYLALKYLAMINE COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF CANCER | SEMMELWEIS UNIV (HU) | 2020-03-18 | — | — | EP | disclosed |
| US-10258598-B2 | Compounds for use in the prevention or treatment of cancer | SEMMELWEIS UNIVERSITY (HU) | 2019-04-16 | — | — | US | disclosed |
| WO-1993012775-A1 | PHARMACEUTICAL COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-07-08 | — | — | WO | disclosed |
| US-5220068-A | N-propyl-1-phenyl-2-alkylamines | CHINOIN GYOGYSZER - ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1993-06-15 | — | — | US | disclosed |
| US-5075338-A | Using aryl secondary amine | CHINOIN GYOGYSZER- ES VERGYESZETI TERMEKEK GYARA RT. (HU) | 1991-12-24 | — | — | US | disclosed |
| EP-0284621-A1 | NEW PSYCHOSTIMULANT AGENT. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1988-10-05 | — | — | EP | disclosed |
| WO-1988002254-A1 | NEW PSYCHOSTIMULANT AGENT | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1988-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170340582-A1 | COMPOUNDS FOR USE IN THE PREVENTION OR TREATMENT OF CANCER | TMSB10, PNMT, HNMT | SIGMAR1 2705/4885MEN1 125/4885KMT2A 504/4885 |
| US-10258598-B2 | Compounds for use in the prevention or treatment of cancer | TMSB10, PNMT, HNMT | SIGMAR1 2675/4885MEN1 140/4885KMT2A 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.