Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690457 | 0.85 | KDM4E (0.58) | KMT2AMAPTHTTALDH1A1HPGD | |
| SCHEMBL11820673 | 0.85 | KDM4E (0.49) | KMT2AMEN1HTR2ASLC6A4MAPT | |
| SCHEMBL31463115 | 0.83 | ELANE (0.60) | KMT2AMEN1MAPTHTTSLC6A3 | |
| SCHEMBL27912018 | 0.82 | CYP1A2 (0.53) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL14893362 | 0.82 | CYP1A2 (0.53) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL10496464 | 0.81 | PTGS2 (0.61) | HTTALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL9629407 | 0.79 | HTT (0.57) | KMT2AMEN1HTR2ASLC6A4MAPT | |
| SCHEMBL2303571 | 0.79 | MAPT (0.60) | KMT2AMEN1HTR2ASLC6A4MAPT | |
| SCHEMBL338196 | 0.79 | PTGS2 (0.68) | HTTALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL29432883 | 0.79 | PTGS2 (0.68) | HTTALDH1A1HPGDTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8779161-B2 | Asenapine maleate | DR. REDDY'S LABORATORIES LIMITED (IN) | 2014-07-15 | — | — | US | disclosed |
| US-20130211099-A1 | ASENAPINE MALEATE | DR. REDDY'S LABORATORIES, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| EP-2582704-A2 | ASENAPINE MALEATE | Dr. Reddy's Laboratories Ltd. (IN) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011159903-A2 | ASENAPINE MALEATE | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-12-22 | — | — | WO | disclosed |
| US-20060154954-A1 | Combinations and use of selected pharmaceutically active compounds | ALTANA PHARMA AG (DE) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130211099-A1 | ASENAPINE MALEATE | CYP3A5, AANAT, ADRA2C | KMT2A 3042/4885MEN1 388/4885HTR2A 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.