Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | MMP13 | P45452 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4589706 | 0.93 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1TSHRKMT2AGAA | |
| SCHEMBL8247534 | 0.81 | VCAM1 (0.59) | SMN1; SMN2ALDH1A1KMT2AGAAHTT | |
| SCHEMBL11174733 | 0.80 | KMT2A (0.57) | SMN1; SMN2ALDH1A1KMT2AGAAHTT | |
| SCHEMBL5461742 | 0.80 | LMNA (0.65) | SMN1; SMN2ALDH1A1TSHRKMT2AGAA | |
| SCHEMBL4589703 | 0.78 | KMT2A (0.54) | SMN1; SMN2ALDH1A1KMT2AGAAHTT | |
| SCHEMBL854501 | 0.77 | KMT2A (0.66) | SMN1; SMN2ALDH1A1TSHRKMT2AGAA | |
| SCHEMBL30213213 | 0.77 | KMT2A (0.66) | SMN1; SMN2ALDH1A1TSHRKMT2AGAA | |
| SCHEMBL10495990 | 0.77 | VCAM1 (0.60) | SMN1; SMN2ALDH1A1KMT2AGAAHTT | |
| SCHEMBL2876686 | 0.76 | KMT2A (0.68) | SMN1; SMN2ALDH1A1TSHRKMT2AGAA | |
| SCHEMBL7650160 | 0.75 | HTT (0.66) | SMN1; SMN2ALDH1A1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713483-A1 | CHEMOKINE INHIBITING PIPERAZINE DERIVATIVES AND THEIR USE TO TREAT MULTIPLE MYELOMA | Schering Aktiengesellschaft (DE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005077372-A1 | CHEMOKINE INHIBITING PIPERAZINE DERIVATIVES AND THEIR USE TO TREAT MULTIPLE MYELOMA | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-08-25 | — | — | WO | disclosed |