Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL28735102 | 0.91 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| Acetic Acid SCHEMBL27674601 | 0.89 | TSHR (0.58) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| Methacrylic Acid SCHEMBL1405658 | 0.86 | ALDH1A1 (0.58) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| Methacrylic Acid SCHEMBL1313296 | 0.86 | ALDH1A1 (0.58) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL17197994 | 0.85 | TSHR (0.79) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL22418810 | 0.85 | TSHR (0.79) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL20094 | 0.85 | TSHR (0.79) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL16684221 | 0.85 | TSHR (0.79) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| Etoglucid SCHEMBL9639500 | 0.85 | ALDH1A1 (0.56) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| Methacrylic Acid SCHEMBL2782095 | 0.85 | ALDH1A1 (0.56) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1810840-A | Carboxyalkyl cellulose polymer network | WEYERHAEUSER CO (US) | 2006-08-02 | — | — | CN | disclosed |
| EP-1676865-A1 | Method of making carboxylkyl cellulose polymer network | Weyerhaeuser Company (US) | 2006-07-05 | — | — | EP | disclosed |
| EP-1676866-A1 | Carboxyalkyl cellulose polymer network | Weyerhaeuser Company (US) | 2006-07-05 | — | — | EP | disclosed |
| CN-1796655-A | Method of making carboxyalkyl cellulose polymer network | WEYERHAEUSER CO (US) | 2006-07-05 | — | — | CN | disclosed |
| US-20060142478-A1 | Carboxyalkyl cellulose polymer network | WEYERHAEUSER COMPANY | 2006-06-29 | — | — | US | disclosed |
| US-20060142480-A1 | Method of making carboxyalkyl cellulose polymer network | WEYERHAEUSER COMPANY | 2006-06-29 | — | — | US | disclosed |