SCHEMBL6025403

SCHEMBL6025403

CCOC(=O)ON=C(C(C)=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.48
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 6/20 0.43
MAPT P10636 4/20 0.43
NPC1 O15118 2/20 0.43
LMNA P02545 1/20 0.40
TSHR P16473 1/20 0.40
GAA P10253 3/20 0.39
RAB9A P51151 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HSP90AA1 P07900 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27836929 0.82 ALDH1A1 (0.49) SMN1; SMN2MEN1KMT2AALDH1A1MAPT
SCHEMBL195608 0.81 ALDH1A1 (0.50) SMN1; SMN2MEN1KMT2AALDH1A1MAPT
SCHEMBL21671033 0.81 ALDH1A1 (0.50) SMN1; SMN2MEN1KMT2AALDH1A1MAPT
SCHEMBL195607 0.81 ALDH1A1 (0.50) SMN1; SMN2MEN1KMT2AALDH1A1MAPT
SCHEMBL3770635 0.81 USP2 (0.57) SMN1; SMN2KMT2AALDH1A1MAPTNPC1
SCHEMBL13538631 0.81 ALDH1A1 (0.53) SMN1; SMN2MEN1KMT2AALDH1A1MAPT
SCHEMBL3770638 0.81 USP2 (0.57) SMN1; SMN2KMT2AALDH1A1MAPTNPC1
Propiophenone SCHEMBL29130147 0.79 KMT2A (0.48) SMN1; SMN2MEN1KMT2AALDH1A1MAPT
SCHEMBL92110 0.78 SMN1; SMN2 (0.57) SMN1; SMN2KMT2AALDH1A1MAPTNPC1
SCHEMBL29130146 0.76 L3MBTL1 (0.46) SMN1; SMN2MEN1KMT2AMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107849415-B Adhesive agent 积水化学工业株式会社 2020-11-06 CN disclosed
EP-3357990-B1 ADHESIVE SEKISUI CHEMICAL CO LTD (JP) 2020-03-04 EP disclosed
US-20180273813-A1 ADHESIVE SEKISUI CHEMICAL CO., LTD. (JP) 2018-09-27 US disclosed
EP-3357990-A1 ADHESIVE Sekisui Chemical Co., Ltd. (JP) 2018-08-08 EP disclosed
EP-1163553-B1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2006-06-14 EP disclosed
US-6806024-B1 MIXTURES OF ADDITION POLYMERS AND ACTIVATORS COMPRISING NITROGEN COMPOUNDS, USED AS SUBSTRATE COATINGS FOR COLOR FILTERS CIBA SPECIALTY CHEMICALS CORPORATION 2004-10-19 US disclosed
EP-1163553-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS Ciba SC Holding AG (CH) 2001-12-19 EP disclosed
WO-2000052530-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-08 WO disclosed