Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800412 | 0.90 | PTGS2 (0.46) | PTGS2PTGS1ABCB11AKR1C3LMNA | |
| SCHEMBL5799148 | 0.87 | PTGS2 (0.52) | PTGS2PTGS1ABCB11AKR1C3LMNA | |
| SCHEMBL6025282 | 0.85 | PTGS1 (0.47) | PTGS2PTGS1ABCB11LMNAALOX5 | |
| SCHEMBL5799040 | 0.84 | PTGS2 (0.46) | PTGS2PTGS1AKR1C3LMNAKDM4E | |
| SCHEMBL5558582 | 0.84 | PTGS2 (0.47) | PTGS2PTGS1AKR1C3LMNAAKR1C2 | |
| SCHEMBL5560264 | 0.84 | PTGS2 (0.35) | PTGS2PTGS1ABCB11AKR1C3KDM4E | |
| SCHEMBL6026386 | 0.82 | HIF1A (0.65) | PTGS2PTGS1ABCB11AKR1C3LMNA | |
| SCHEMBL5553721 | 0.82 | AKR1C3 (0.44) | PTGS2PTGS1AKR1C3LMNAKDM4E | |
| SCHEMBL6025157 | 0.81 | PTGS1 (0.45) | PTGS2PTGS1ABCB11LMNAMEN1 | |
| SCHEMBL6025108 | 0.80 | CNR2 (0.47) | PTGS2PTGS1LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628532-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | Microbia, Inc. (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004108085-A2 | METHODS FOR THE PROTECTION OF MEMORY AND COGNITION | MICROBIA, INC. (US) | 2004-12-16 | — | — | WO | disclosed |