Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | RXRG | P48443 | 2/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | TLR3 | O15455 | 1/20 | 0.39 |
| ▸ | TLR5 | O60602 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3081107 | 0.81 | KIF11 (0.38) | MAPTCNR1CNR2CYP2D6KIF11 | |
| SCHEMBL1614610 | 0.79 | RXRA (0.43) | MAPTMAPK1TDP1L3MBTL1SGMS2 | |
| SCHEMBL1614851 | 0.79 | RXRA (0.43) | MAPTMAPK1TDP1L3MBTL1SGMS2 | |
| SCHEMBL28524935 | 0.78 | CNR1 (0.38) | MAPTCNR1CNR2GAAKIF11 | |
| SCHEMBL3081113 | 0.78 | CNR1 (0.38) | MAPTCNR1CNR2GAAKIF11 | |
| SCHEMBL27595906 | 0.75 | KIF11 (0.57) | CYP2D6GAAKIF11 | |
| SCHEMBL5868580 | 0.75 | KIF11 (0.57) | CYP2D6GAAKIF11 | |
| SCHEMBL28062215 | 0.75 | KIF11 (0.57) | CYP2D6GAAKIF11 | |
| SCHEMBL27676286 | 0.75 | KIF11 (0.57) | CYP2D6GAAKIF11 | |
| SCHEMBL17817860 | 0.75 | KIF11 (0.57) | CYP2D6GAAKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622602-A4 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | GEN HOSPITAL CORP (US) | 2006-06-21 | — | — | EP | disclosed |
| EP-1622602-A2 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | THE GENERAL HOSPITAL CORPORATION (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004093650-A2 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | THE GENERAL HOSPITAL CORPORATION (US) | 2004-11-04 | — | — | WO | disclosed |