Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TLR3 | O15455 | 1/20 | 0.38 |
| ▸ | TLR5 | O60602 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1614851 | 1.00 | RXRA (0.43) | RXRARXRBRXRGLIPEMAPT | |
| SCHEMBL6026359 | 0.79 | MAPT (0.43) | RXRARXRBRXRGLIPEMAPT | |
| SCHEMBL10882700 | 0.74 | RXRA (0.50) | RXRARXRBRXRGLIPEMAPT | |
| SCHEMBL16459448 | 0.74 | CETP (0.47) | MAPK1TDP1L3MBTL1CETPMBOAT4 | |
| SCHEMBL8709296 | 0.73 | MBOAT4 (0.45) | MAPK1TDP1L3MBTL1CETPBCHE | |
| SCHEMBL12745448 | 0.73 | HTR1A (0.59) | LIPEMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL1614849 | 0.73 | CETP (0.47) | MAPK1TDP1L3MBTL1CETPMBOAT4 | |
| SCHEMBL1614607 | 0.73 | CETP (0.47) | MAPK1TDP1L3MBTL1CETPMBOAT4 | |
| SCHEMBL6811511 | 0.71 | MBOAT4 (0.43) | MAPK1TDP1L3MBTL1CETPBCHE | |
| SCHEMBL8991579 | 0.71 | GAA (0.45) | LIPEMAPTMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10322103-B2 | Compositions for prevention/prophylactic treatment of poison ivy dermatitis | UNIVERSITY OF MISSISSIPPI (US) | 2019-06-18 | — | — | US | disclosed |
| US-20180078520-A1 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | UNIVERSITY OF MISSISSIPPI | 2018-03-22 | — | — | US | disclosed |
| EP-3274322-A1 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | The University Of Mississippi (US) | 2018-01-31 | — | — | EP | disclosed |
| WO-2016160090-A1 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | THE UNIVERSITY OF MISSISSIPPI (US) | 2016-10-06 | — | — | WO | disclosed |
| US-9408822-B2 | Compositions for prevention/prophylactic treatment of poison ivy dermatitis | THE UNIVERSITY OF MISSISSIPPI (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150202176-A1 | Compositions for Prevention/Prophylactic Treatment of Poison Ivy Dermatitis | THE UNIVERSITY OF MISSISSIPPI | 2015-07-23 | — | — | US | disclosed |
| US-9029417-B2 | Compositions for prevention/prophylactic treatment of poison ivy dermatitis | THE UNIVERSITY OF MISSISSIPPI (US) | 2015-05-12 | — | — | US | disclosed |
| US-20130303582-A1 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | THE UNIVERSITY OF MISSISSIPPI | 2013-11-14 | — | — | US | disclosed |
| US-8486998-B2 | Compositions for prevention/prophylactic treatment of poison ivy dermatitis | THE UNIVERSITY OF MISSISSIPPI (US) | 2013-07-16 | — | — | US | disclosed |
| US-20110086900-A1 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | THE UNIVERSITY OF MISSISSIPPI | 2011-04-14 | — | — | US | disclosed |
| WO-2009146131-A2 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | THE UNIVERSITY OF MISSISSIPPI (US) | 2009-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303582-A1 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | UGT1A3, IL33, ITCH | RXRA 3351/4885RXRB 3166/4885RXRG 3311/4885 |
| US-20150202176-A1 | Compositions for Prevention/Prophylactic Treatment of Poison Ivy Dermatitis | UGT1A3, IL33, ITCH | RXRA 3351/4885RXRB 3166/4885RXRG 3311/4885 |
| US-20180078520-A1 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | UGT1A3, ITCH, UGT1A1 | RXRA 4006/4885RXRB 3818/4885RXRG 4003/4885 |
| US-10322103-B2 | Compositions for prevention/prophylactic treatment of poison ivy dermatitis | UGT1A3, ITCH, UGT1A1 | RXRA 4006/4885RXRB 3818/4885RXRG 4003/4885 |
| US-20110086900-A1 | COMPOSITIONS FOR PREVENTION/PROPHYLACTIC TREATMENT OF POISON IVY DERMATITIS | UGT1A3, IL33, ITCH | RXRA 3351/4885RXRB 3166/4885RXRG 3311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.