Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29008018 | 0.78 | TSHR (0.45) | ATMMAPTKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29008069 | 0.77 | TSHR (0.44) | ATMMAPTKDM4EMEN1KMT2A | |
| SCHEMBL10731063 | 0.76 | RAB9A (0.40) | ATMMAPTKDM4EMEN1KMT2A | |
| SCHEMBL28549992 | 0.74 | L3MBTL1 (0.37) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL4626316 | 0.71 | KDM4E (0.32) | ATMMAPTKDM4EMEN1KMT2A | |
| SCHEMBL4691963 | 0.71 | CA12 (0.50) | MAPTKDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL30719997 | 0.69 | KDM4E (0.68) | ATMMAPTKDM4EMEN1KMT2A | |
| SCHEMBL926927 | 0.69 | KDM4E (0.68) | ATMMAPTKDM4EMEN1KMT2A | |
| SCHEMBL668192 | 0.69 | CA12 (0.61) | MAPTKDM4EMEN1KMT2AHSP90AA1 | |
| SCHEMBL16647662 | 0.69 | MRGPRX4 (0.51) | MAPTKDM4EMEN1KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597253-B1 | COMPOUNDS AND METHODS OF TREATING CELL PROLIFERATIVE DISEASES, RETINOPATHIES AND ARTHRITIS | EXONHIT THERAPEUTICS SA (FR) | 2006-08-09 | — | — | EP | disclosed |