Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | FABP1 | P07148 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026140 | 1.00 | LTB4R (0.45) | LTB4RLTB4R2PPARAALBCNR2 | |
| Velaresol SCHEMBL61907 | 0.99 | PPARA (0.44) | LTB4RLTB4R2PPARAALBCNR2 | |
| SCHEMBL6026502 | 0.94 | TSHR (0.44) | LTB4RLTB4R2PPARAALDH1A1LMNA | |
| SCHEMBL6026753 | 0.87 | LMNA (0.42) | LTB4RLTB4R2CNR2ALDH1A1CNR1 | |
| Velaresol SCHEMBL11157225 | 0.85 | CNR2 (0.45) | CNR2ALDH1A1CNR1PTGDR2 | |
| Velaresol SCHEMBL11149918 | 0.84 | PPARG (0.45) | PPARACNR2ALDH1A1CNR1LMNA | |
| SCHEMBL10921040 | 0.83 | SMN1; SMN2 (0.42) | LTB4RLTB4R2PPARACNR2ALDH1A1 | |
| SCHEMBL11149422 | 0.83 | LMNA (0.55) | LTB4RLTB4R2PPARACNR2ALDH1A1 | |
| SCHEMBL10926348 | 0.83 | CNR1 (0.43) | CNR2ALDH1A1CNR1 | |
| SCHEMBL24080812 | 0.82 | GAA (0.50) | CNR2ALDH1A1CNR1LMNAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074770-B1 | Method of DNA vaccination | SMITHKLINE BEECHAM CORPORATION (US) | 2006-07-11 | — | — | US | claimed |
| CN-1326358-A | Method of DNA vaccination | GLAXO GROUP LTD (GB) | 2001-12-12 | — | — | CN | claimed |
| EP-1107785-A1 | METHOD OF DNA VACCINATION | GLAXO GROUP LIMITED (GB) | 2001-06-20 | — | — | EP | claimed |
| WO-2000012121-A1 | METHOD OF DNA VACCINATION | GLAXO GROUP LIMITED (GB) | 2000-03-09 | — | — | WO | claimed |
| US-7074770-B1 | Method of DNA vaccination | SMITHKLINE BEECHAM CORPORATION (US) | 2006-07-11 | — | — | US | disclosed |
| CN-1326358-A | Method of DNA vaccination | GLAXO GROUP LTD (GB) | 2001-12-12 | — | — | CN | disclosed |
| EP-1107785-A1 | METHOD OF DNA VACCINATION | GLAXO GROUP LIMITED (GB) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012121-A1 | METHOD OF DNA VACCINATION | GLAXO GROUP LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |
| EP-0614357-A1 | IMMUNOPOTENTIATORY AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-09-14 | — | — | EP | disclosed |
| WO-1994007479-A2 | IMMUNOPOTENTIATORY AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-04-14 | — | — | WO | disclosed |
| EP-0054924-B1 | PHARMACEUTICAL COMPOUNDS, THEIR PREPARATION AND USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-08-06 | — | — | EP | disclosed |
| US-4535183-A | PALLIATION OF SICKLE CELL ANEMIA, RESPIRATORY DISORDERS, HYPOXIA, RADIOSENSITIZATION OF TUMORS | BURROUGHS WELLCOME CO. (US) | 1985-08-13 | — | — | US | disclosed |
| EP-0054924-A2 | Pharmaceutical compounds, their preparation and use | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-06-30 | — | — | EP | disclosed |