Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027006 | 0.99 | LTA4H (0.44) | CNR1CNR2LTA4HF2RL3CYP4F2 | |
| SCHEMBL10919678 | 0.88 | ESR2 (0.43) | LTA4HF2RL3CYP4F2CYP4A11PTPN1 | |
| SCHEMBL11149449 | 0.86 | ESR2 (0.44) | LTA4HCYP4F2CYP4A11PTPN1 | |
| SCHEMBL12610480 | 0.85 | CNR1 (0.47) | CNR1CNR2F2RL3CYP4F2CYP4A11 | |
| SCHEMBL200763 | 0.83 | TDP1 (0.46) | LTA4HCYP4F2CYP4A11TDP1 | |
| SCHEMBL6027074 | 0.83 | HTR1A (0.43) | LTA4HALDH1A1TDP1 | |
| SCHEMBL6027258 | 0.83 | LTB4R (0.45) | CNR1CNR2ALDH1A1 | |
| SCHEMBL6026140 | 0.83 | LTB4R (0.45) | CNR1CNR2ALDH1A1 | |
| SCHEMBL24080812 | 0.83 | GAA (0.50) | CNR1CNR2PTPN1ALDH1A1CYP3A4 | |
| SCHEMBL7318619 | 0.82 | L3MBTL1 (0.54) | LTA4HALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054924-B1 | PHARMACEUTICAL COMPOUNDS, THEIR PREPARATION AND USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-08-06 | — | — | EP | disclosed |
| EP-0054924-A2 | Pharmaceutical compounds, their preparation and use | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-06-30 | — | — | EP | disclosed |