Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | RARA | P10276 | 4/20 | 0.44 |
| ▸ | RARB | P10826 | 4/20 | 0.44 |
| ▸ | RARG | P13631 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | BLVRB | P30043 | 1/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616240 | 0.81 | CYP26A1 (0.55) | CYP26A1KMT2ACYP3A4RARARARB | |
| SCHEMBL1615594 | 0.77 | CYP26A1 (0.60) | CYP26A1KMT2ACYP3A4RARARARB | |
| SCHEMBL1614827 | 0.74 | CYP26A1 (0.58) | CYP26A1KMT2ACYP3A4RARARARB | |
| SCHEMBL1616029 | 0.72 | CYP26A1 (0.60) | CYP26A1KMT2ACYP3A4RARARARB | |
| SCHEMBL1615912 | 0.71 | RARB (0.65) | CYP26A1KMT2ACYP3A4RARARARB | |
| SCHEMBL8839196 | 0.70 | SMN1; SMN2 (0.51) | CYP26A1KMT2ACYP3A4RARARARB | |
| SCHEMBL10459708 | 0.69 | RXRA (0.56) | CYP26A1KMT2ACYP3A4RARARARB | |
| SCHEMBL8165528 | 0.69 | PDE4B (0.43) | CYP26A1KMT2ACYP3A4RARARARB | |
| SCHEMBL9446451 | 0.69 | RARA (0.60) | CYP26A1KMT2ACYP3A4RARARARB | |
| SCHEMBL7896396 | 0.68 | RXRA (0.58) | CYP26A1KMT2ACYP3A4RARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692097-A1 | TRICYCLIC HYDROXAMATE AND BENZAMIDE DERIVATIVES, COMPOSITIONS AND METHODS | Exonhit Therapeutics SA (FR) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005058803-A1 | TRICYCLIC HYDROXAMATE AND BENZAMIDE DERIVATIVES, COMPOSITIONS AND METHODS | EXONHIT THERAPEUTICS SA (FR) | 2005-06-30 | — | — | WO | disclosed |