Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966040 | 0.85 | POLB (0.60) | POLBHTTLMNATLR8L3MBTL1 | |
| SCHEMBL10408180 | 0.83 | POLB (0.46) | POLBHTTLMNATLR8L3MBTL1 | |
| SCHEMBL5605579 | 0.82 | LMNA (0.62) | POLBHTTLMNATLR8L3MBTL1 | |
| SCHEMBL309485 | 0.82 | TLR8 (0.53) | POLBHTTTLR8L3MBTL1KDM4E | |
| SCHEMBL25366175 | 0.81 | TLR8 (0.47) | POLBHTTLMNATLR8L3MBTL1 | |
| SCHEMBL10407866 | 0.79 | POLB (0.54) | POLBTLR8L3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL20917753 | 0.79 | POLB (0.43) | POLBHTTLMNATLR8L3MBTL1 | |
| SCHEMBL1438701 | 0.79 | POLB (0.40) | POLBHTTLMNATLR8L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9224499 | 0.79 | AR (0.42) | POLBHTTLMNASMN1; SMN2TSHR | |
| SCHEMBL10408672 | 0.78 | LIPG (0.49) | POLBTLR8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644722-A1 | OPTIMIZED DETERMINATION OF VOLTAGE CHANGES USING A VOLTAGE-SENSITIVE DYE | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005001448-A1 | OPTIMIZED DETERMINATION OF VOLTAGE CHANGES USING A VOLTAGE-SENSITIVE DYE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2005-01-06 | — | — | WO | disclosed |