Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.47 |
| ▸ | CA2 | P00918 | 10/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | CA6 | P23280 | 3/20 | 0.47 |
| ▸ | CA5A | P35218 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL307454 | 0.89 | CA2 (0.56) | CA1CA2CA9CA6CA5A | |
| SCHEMBL29520231 | 0.89 | CA2 (0.56) | CA1CA2CA9CA6CA5A | |
| SCHEMBL28298105 | 0.87 | CA2 (0.54) | CA1CA2CA9CA6CA5A | |
| Hydrochloric Acid SCHEMBL21326134 | 0.87 | CA2 (0.54) | CA1CA2CA9CA6CA5A | |
| Hydrochloric Acid SCHEMBL7460198 | 0.87 | CA2 (0.54) | CA1CA2CA9CA6CA5A | |
| Formic Acid SCHEMBL14247387 | 0.85 | PTGES2 (0.55) | CA1CA2CA9CA6CA5A | |
| Trifluoroacetic Acid SCHEMBL27848730 | 0.79 | CA2 (0.45) | CA1CA2CA9CA6CA5A | |
| SCHEMBL28226379 | 0.78 | CA2 (0.48) | CA1CA2CA9CA6CA5A | |
| Formic Acid SCHEMBL14247448 | 0.77 | PTGES2 (0.43) | CA1CA2CA9CA12PTGES2 | |
| Formic Acid SCHEMBL29730758 | 0.76 | CA2 (0.47) | CA1CA2CA9CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709007-A1 | N-4-(6-(HETEO)ARYL-PYRIMIDIN-4-YLAMINOPHENYL)-BENZENESULFONAMIDES AS KINASE INHIBITORS | Altana Pharma AG (DE) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005070900-A1 | N-4-(6- (HETEO) ARYL-PYRIMIDIN-4-YLAMINOPHENYL) -BEZENESULFONAMIDES AS KINASE INHIBITORS | ALTANA PHARMA AG (DE) | 2005-08-04 | — | — | WO | disclosed |