SCHEMBL29520231

SCHEMBL29520231

NS(=O)(=O)c1ccccc1F

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 13/20 0.56
CA1 P00915 10/20 0.56
CA9 Q16790 9/20 0.56
CA12 O43570 6/20 0.56
CA6 P23280 4/20 0.56
CA4 P22748 3/20 0.56
CA5A P35218 3/20 0.56
CA7 P43166 3/20 0.56
CA5B Q9Y2D0 3/20 0.56
CA14 Q9ULX7 2/20 0.56
CYP2C9 P11712 1/20 0.56
PTGES2 Q9H7Z7 4/20 0.53
CA3 P07451 1/20 0.44
PLA2G7 Q13093 1/20 0.44
CA13 Q8N1Q1 1/20 0.44
LDHA P00338 1/20 0.43
CDK2 P24941 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL307454 1.00 CA2 (0.56) CA2CA1CA9CA12CA6
Hydrochloric Acid SCHEMBL7460198 0.98 CA2 (0.54) CA2CA1CA9CA12CA6
Hydrochloric Acid SCHEMBL21326134 0.98 CA2 (0.54) CA2CA1CA9CA12CA6
Formic Acid SCHEMBL6027486 0.89 CA1 (0.47) CA2CA1CA9CA12CA6
SCHEMBL2568298 0.82 ALOX5AP (0.49) CA2CA1CA9CA12CA6
SCHEMBL2051439 0.82 NFE2L2 (0.43)
SCHEMBL789494 0.81 PTGES2 (0.64) CA2CA1CA9CA12CA6
SCHEMBL30307782 0.81 PTGES2 (0.64) CA2CA1CA9CA12CA6
SCHEMBL202947 0.81 CA2 (0.70) CA2CA1CA9CA12CA6
Hydrochloric Acid SCHEMBL9955460 0.79 PTGES2 (0.62) CA2CA1CA9CA12CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250145589-A1 PYRIDINE DERIVATIVE AND USE THEREOF SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) 2025-05-08 US disclosed
WO-2025006659-A1 MIXTURES OF BIXLOZONE WITH PHOTOSYSTEM I ELECTRON DIVERTERS FMC CORPORATION (US) 2025-01-02 WO disclosed
CN-117945962-A Synthesis method of bicalutamide 中国人民大学 2024-04-30 CN disclosed
WO-2023028077-A1 SODIUM CHANNEL INHIBITORS AND METHODS OF DESIGNING SAME GENENTECH, INC. (US) 2023-03-02 WO disclosed
EP-4077289-A1 2-AMINO-N-(AMINO-OXO-ARYL-LAMBDA6-SULFANYLIDENE)ACETAMIDE COMPOUNDS AND THEIR THERAPEUTIC USE Oxford Drug Design Limited (GB) 2022-10-26 EP disclosed
CN-109153649-B Allosteric modulators of nicotinic acetylcholine receptors 默沙东公司 2022-04-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250145589-A1 PYRIDINE DERIVATIVE AND USE THEREOF KRAS, NRAS, BRAF CA2 3676/4885CA1 3768/4885CA9 2805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.