SCHEMBL307454

SCHEMBL307454

NS(=O)(=O)c1ccccc1F

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 13/20 0.56
CA1 P00915 10/20 0.56
CA9 Q16790 9/20 0.56
CA12 O43570 6/20 0.56
CA6 P23280 4/20 0.56
CA4 P22748 3/20 0.56
CA5A P35218 3/20 0.56
CA7 P43166 3/20 0.56
CA5B Q9Y2D0 3/20 0.56
CA14 Q9ULX7 2/20 0.56
CYP2C9 P11712 1/20 0.56
PTGES2 Q9H7Z7 4/20 0.53
CA3 P07451 1/20 0.44
PLA2G7 Q13093 1/20 0.44
CA13 Q8N1Q1 1/20 0.44
LDHA P00338 1/20 0.43
CDK2 P24941 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29520231 1.00 CA2 (0.56) CA2CA1CA9CA12CA6
Hydrochloric Acid SCHEMBL7460198 0.98 CA2 (0.54) CA2CA1CA9CA12CA6
Hydrochloric Acid SCHEMBL21326134 0.98 CA2 (0.54) CA2CA1CA9CA12CA6
Formic Acid SCHEMBL6027486 0.89 CA1 (0.47) CA2CA1CA9CA12CA6
SCHEMBL2568298 0.82 ALOX5AP (0.49) CA2CA1CA9CA12CA6
SCHEMBL2051439 0.82 NFE2L2 (0.43)
SCHEMBL789494 0.81 PTGES2 (0.64) CA2CA1CA9CA12CA6
SCHEMBL30307782 0.81 PTGES2 (0.64) CA2CA1CA9CA12CA6
SCHEMBL202947 0.81 CA2 (0.70) CA2CA1CA9CA12CA6
Hydrochloric Acid SCHEMBL9955460 0.79 PTGES2 (0.62) CA2CA1CA9CA12CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4593598-A1 STORAGE-STABLE COMPOSITIONS INCLUDING BIXLOZONE AND BEFLUBUTAMID FMC Corporation (US) 2025-08-06 EP claimed
US-12331026-B2 Sulfonamido derivatives as cyclin-dependent kinase 2 inhibitors NIKANG THERAPEUTICS, INC. (US) 2025-06-17 US claimed
CN-119219810-A Ionic polymer and preparation method and application thereof 佛山绿动氢能科技有限公司 2024-12-31 CN claimed
CN-118507836-B Electrolyte for secondary lithium metal battery 深圳欣界能源科技有限公司 2024-09-17 CN claimed
CN-118507836-A Electrolyte for secondary lithium metal battery 深圳欣界能源科技有限公司 2024-08-16 CN claimed
CN-113795254-B Pyrazolopyridine compounds for IRE1 inhibition 奥普提卡拉公司 2024-08-09 CN claimed
US-20240262801-A1 COMPOUNDS HAVING 5-(2-FLUORO-6-HYDROXYPHENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE AS INHIBITORS OF PROTEIN KINASE PHOSPHATASE ENZYMES MONDEGO BIO, LDA. (PT) 2024-08-08 US claimed
CN-118324773-A Rhodamine derivative and preparation method and application thereof 陕西师范大学 2024-07-12 CN claimed
WO-2024115549-A1 ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2024-06-06 WO claimed
WO-2024073019-A1 STORAGE-STABLE COMPOSITIONS INCLUDING BIXLOZONE AND B EFLUB UT AMID FMC CORPORATION (US) 2024-04-04 WO claimed
WO-1995020585-A1 DIASTEREOSELECTIVE PROCESS LEADING TO A KEY INTERMEDIATE FOR THE PREPARATION OF FLUORINATED REVERSE TRANSCRIPTASE INHIBITORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1995-08-03 WO claimed
EP-0447013-B1 Fluorobenzene sulphonamides SCHERING AG (DE) 1994-08-03 EP claimed
CN-1090279-A Be used for the treatment of HIV and other retroviral pyran-2-ones and 5,6-dihydropyrane-2-ketone UPJOHN CO (US) 1994-08-03 CN claimed
EP-0420815-B1 Process for the preparation of 2-(2-haloethylthio)-phenylsulfonamides CIBA GEIGY AG (CH) 1994-01-19 EP claimed
US-5210290-A NMR diagnostic aid SCHERING AKTIENGESELLSCHAFT (DE) 1993-05-11 US claimed
US-5166430-A PROCESS FOR THE PREPARATION OF 2-(2-HALOGENOETHYLTHIO)-PHENYLSULFONAMIDES CIBA-GEIGY CORPORATION (US) 1992-11-24 US claimed
EP-0447013-A1 Fluorobenzene sulphonamides SCHERING AKTIENGESELLSCHAFT (DE) 1991-09-18 EP claimed
EP-0420815-A1 Process for the preparation of 2-(2-haloethylthio)-phenylsulfonamides CIBA-GEIGY AG (CH) 1991-04-03 EP claimed
EP-0132230-B1 PROCESS FOR THE PREPARATION OF SULFONYL UREA CIBA-GEIGY AG (CH) 1988-10-05 EP claimed
EP-0132230-A2 Process for the preparation of sulfonyl urea CIBA-GEIGY AG (CH) 1985-01-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240262801-A1 COMPOUNDS HAVING 5-(2-FLUORO-6-HYDROXYPHENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE AS INHIBITORS OF PROTEIN KINASE PHOSPHATASE ENZYMES PPM1A, TH, PPM1G CA2 588/4885CA1 2273/4885CA9 1552/4885
US-12331026-B2 Sulfonamido derivatives as cyclin-dependent kinase 2 inhibitors CDK2, CCNK, CCNI CA2 2801/4885CA1 3540/4885CA9 3000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.