Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.64 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | KDM4A | O75164 | 4/20 | 0.43 |
| ▸ | KDM5C | P41229 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28608865 | 0.88 | PLAU (0.60) | PLAUGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28216401 | 0.87 | PLAU (0.52) | PLAUGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL6978513 | 0.80 | PLAU (0.63) | PLAUGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL17053153 | 0.77 | PLAU (0.59) | PLAUGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30527962 | 0.77 | PLAU (0.59) | PLAUGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2671644 | 0.77 | PLAU (0.59) | PLAUGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL16246728 | 0.76 | PLAU (0.38) | PLAUKDM4EIGFBP3APAF1NSD2 | |
| Trifluoroacetic Acid SCHEMBL6978086 | 0.76 | PLAU (0.55) | PLAUGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4279451 | 0.75 | RAB9A (0.50) | PLAUKDM4EALDH1A1MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6999130 | 0.75 | PLAU (0.57) | PLAUGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107949559-A | Bicyclic fused heteroaryl or aryl compounds as IRAK4 modulators | 辉瑞公司 | 2018-04-20 | — | — | CN | disclosed |
| US-20060004041-A1 | Compounds for treatment of neurodegenerative diseases | ENVIVO PHARMACEUTICALS, INC. | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004041-A1 | Compounds for treatment of neurodegenerative diseases | HDAC5, HDAC6, HDAC3 | PLAU 3982/4885GABRP 3035/4885GABRD 4387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.