Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.79 |
| ▸ | APAF1 | O14727 | 1/20 | 0.79 |
| ▸ | NPC1 | O15118 | 1/20 | 0.79 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | HTT | P42858 | 1/20 | 0.79 |
| ▸ | RAB9A | P51151 | 1/20 | 0.79 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.79 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.79 |
| ▸ | FDPS | P14324 | 16/20 | 0.41 |
| ▸ | PON1 | P27169 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34969 | 0.98 | MEN1 (0.81) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL2580666 | 0.96 | MEN1 (0.79) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL14841603 | 0.96 | MEN1 (0.79) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| SCHEMBL358571 | 0.96 | MEN1 (0.79) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL232599 | 0.96 | SMN1; SMN2 (0.85) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Fluoride Ion SCHEMBL1898684 | 0.96 | MEN1 (0.79) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Iodide SCHEMBL3697966 | 0.96 | MEN1 (0.79) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Hydrochloric Acid SCHEMBL36719 | 0.96 | MEN1 (0.79) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Hydrochloric Acid SCHEMBL20957483 | 0.96 | MEN1 (0.79) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 | |
| Bromide SCHEMBL30954387 | 0.96 | SMN1; SMN2 (0.85) | MEN1HSP90AA1KMT2ASMN1; SMN2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12272495-B2 | Systems and methods for improved supercapacitors with ionic liquid electrolytes | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2025-04-08 | — | — | US | claimed |
| CN-114249722-B | Preparation method of moxifloxacin hydrochloride | 常州方圆制药有限公司 | 2024-09-03 | — | — | CN | claimed |
| CN-117983023-A | Maleic anhydride process tail gas recycling device, maleic anhydride process tail gas recycling method and application | 中国石油化工股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| EP-3973550-B1 | PEPTIDE IONOGEL COMPOSITION, METHODS AND USES THEREOF | UNIV NOVA DE LISBOA (PT) | 2024-01-31 | — | — | EP | claimed |
| WO-2023123753-A1 | METHOD FOR CATALYTIC SYNTHESIS OF ACCELERATOR CBS BY USING IONIC LIQUID PROTECTIVE AGENT | 科迈化工股份有限公司 | 2023-07-06 | — | — | WO | claimed |
| CN-115772128-A | Preparation method and application of 2,4,6-trisubstituted pyrimidine compound | 药大制药有限公司 | 2023-03-10 | — | — | CN | claimed |
| US-11417913-B2 | Ionic liquid gel for electrolyte, method of and ink for making the same, and printed batteries including such ionic liquid gels and/or electrolytes | IMPRINT ENERGY, INC. (US) | 2022-08-16 | — | — | US | claimed |
| CN-114807611-A | Method for gently stripping circuit board metal coating and separating and recovering metal/nonmetal components in substrate | 上海第二工业大学 | 2022-07-29 | — | — | CN | claimed |
| CN-114752107-A | Method for recycling and preparing high-performance PET composite material from waste PET film | 桐乡市思远环保科技有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-114249722-A | Preparation method of moxifloxacin hydrochloride | 常州方圆制药有限公司 | 2022-03-29 | — | — | CN | claimed |
| US-9484158-B2 | Graphene-ionic liquid composites | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-11-01 | — | — | US | claimed |
| US-20160145229-A1 | EXTRACTION SEPARATION METHOD OF A FLAVONE COMPONENT BASED ON GRAPHENE | Shenzhen Violin Technology Co.,Ltd. | 2016-05-26 | — | — | US | claimed |
| US-20140127456-A1 | METHODS OF IMPROVING LONG RANGE ORDER IN SELF-ASSEMBLY OF BLOCK COPOLYMER FILMS WITH IONIC LIQUIDS AND MATERIALS PRODUCED THEREFROM | MICRON TECHNOLOGY, INC. (US) | 2014-05-08 | — | — | US | claimed |
| US-8641914-B2 | Methods of improving long range order in self-assembly of block copolymer films with ionic liquids | MICRON TECHNOLOGY, INC. (US) | 2014-02-04 | — | — | US | claimed |
| US-8420732-B2 | Polybenzimidazole solution in an ionic liquid | PBI PERFORMANCE PRODUCTS, INC. (US) | 2013-04-16 | — | — | US | claimed |
| US-20120142830-A1 | POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID | DAWKINS BOBBY G (US) | 2012-06-07 | — | — | US | claimed |
| US-20110152413-A1 | POLYBENZIMIDAZOLE SOLUTION IN AN IONIC LIQUID | PBI PERFORMANCE PRODUCTS, INC. | 2011-06-23 | — | — | US | claimed |
| EP-1866957-A1 | SELECTIVE WET ETCHING OF METAL NITRIDES | SACHEM, INC. (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2006110279-A1 | SELECTIVE WET ETCHING OF METAL NITRIDES | SACHEM, INC. (US) | 2006-10-19 | — | — | WO | claimed |
| US-20060226122-A1 | Selective wet etching of metal nitrides | NATIONAL CITY BANK, AS AGENT | 2006-10-12 | — | — | US | claimed |