Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5397142 | 0.84 | ALDH1A1 (0.50) | SRCHIF1ALIPGSMN1; SMN2LMNA | |
| SCHEMBL27518575 | 0.80 | TDP1 (0.49) | SRCLIPGSMN1; SMN2ALOX5 | |
| SCHEMBL30440577 | 0.79 | SRC (0.51) | KDM4ESRCMKNK1CHEK2HIF1A | |
| SCHEMBL22557366 | 0.77 | ADRA2A (0.38) | KDM4EGRM5SMN1; SMN2LMNANPC1 | |
| SCHEMBL18131222 | 0.77 | CHEK2 (0.40) | KDM4EGRM5MKNK1CHEK2SMN1; SMN2 | |
| SCHEMBL18661930 | 0.76 | IDO1 (0.57) | KDM4ESMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL17674283 | 0.76 | KDM4E (0.42) | KDM4ESMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL11917561 | 0.75 | LMNA (0.55) | SRCHIF1ALIPGSMN1; SMN2LMNA | |
| SCHEMBL6223872 | 0.75 | SMN1; SMN2 (0.59) | KDM4ESMN1; SMN2LMNANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7607601 | 0.73 | SMN1; SMN2 (0.58) | KDM4ESMN1; SMN2LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720829-A1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005090292-A1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |