Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.54 |
| ▸ | TTPA | P49638 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675007 | 1.00 | CYP3A4 (0.63) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL5674832 | 1.00 | CYP3A4 (0.63) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| Ethane SCHEMBL4283975 | 0.99 | CYP3A4 (0.62) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL9655733 | 0.87 | CYP3A4 (0.58) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL3090662 | 0.86 | ALOX5 (0.70) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL13156991 | 0.86 | ALOX5 (0.70) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL13566290 | 0.86 | ALOX5 (0.70) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL11707684 | 0.85 | ALOX5 (0.51) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL11706911 | 0.85 | ALOX5 (0.51) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL8600719 | 0.85 | PTGS1 (0.51) | CYP3A4TSHRPTGS1PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9976084-B2 | Liquid crystal composition, antioxidant and liquid crystal display device | JNC CORPORATION (JP) | 2018-05-22 | — | — | US | disclosed |
| US-20140183409-A1 | LIQUID CRYSTAL COMPOSITION, ANTIOXIDANT AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2014-07-03 | — | — | US | disclosed |
| US-7038067-B2 | Process for synthesizing d-tocotrienols from 2-vinylchromane compound | YASOO HEALTH, INC. (US) | 2006-05-02 | — | — | US | disclosed |
| US-20050124688-A1 | Process for synthesizing d-tocotrienols from 2-vinylchromane compound | YASOO HEALTH, INC. | 2005-06-09 | — | — | US | disclosed |
| US-20050124687-A1 | Process for synthesizing d-tocotrienols | COULADOUROS ELIAS A (GR) | 2005-06-09 | — | — | US | disclosed |
| WO-2005035491-A2 | PROCESS FOR SYNTHESIZING d-TOCOTRIENOLS FROM 2- VINYLCHROMANE COMPOUND | YASOO HEALTH, INC. (US) | 2005-04-21 | — | — | WO | disclosed |
| WO-2005035490-A2 | PROCESS FOR SYNTHESIZING d-TOCOTRIENOLS | YASOO HEALTH, INC. (US) | 2005-04-21 | — | — | WO | disclosed |
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| US-5925673-A | PREVENTING OR ALLEVIATING DAMAGE TO MAMMALIAN TISSUES | ALCON LABORATORIES, INC. (US) | 1999-07-20 | — | — | US | disclosed |
| WO-1999032474-A1 | BENZOFURANS AND BENZOPYRANS AS CYTOPROTECTIVE AGENTS | ALCON LABORATORIES, INC. (US) | 1999-07-01 | — | — | WO | disclosed |
| EP-0283946-A1 | Novel intermediates useful in preparing vitamin E | F. HOFFMANN-LA ROCHE AG (CH) | 1988-09-28 | — | — | EP | disclosed |
| US-4752646-A | 2-halochromans | HOFFMANN-LA ROCHE INC. (US) | 1988-06-21 | — | — | US | disclosed |
| EP-0235510-A2 | 3,4-Dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran derivatives and processes for their preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-09-09 | — | — | EP | disclosed |
| US-4208333-A | Preparation of chroman-2-acetic acids | HOFFMANN-LA ROCHE INC. (US) | 1980-06-17 | — | — | US | disclosed |
| US-4192816-A | Mixtures of 3-pentenenitriles and 3-methylene-pentanenitriles | HOFFMANN-LA ROCHE INC. (US) | 1980-03-11 | — | — | US | disclosed |
| US-4186138-A | Preparation of chroman-2-acetic acids | HOFFMANN-LA ROCHE INC. (US) | 1980-01-29 | — | — | US | disclosed |
| US-4026907-A | INTERMEDIATES FOR ALPHA-TOCOPHEROL | HOFFMANN-LA ROCHE INC. (US) | 1977-05-31 | — | — | US | disclosed |
| US-4018799-A | INTERMEDIATES FOR TOCOPHEROL | HOFFMANN-LA ROCHE INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-4003919-A | INTERMEDIATES FOR ALPHA-TOCOPHEROL | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-3947473-A | (6-HYDROXY-CHROMAN-2-YL) CARBOXYLIC ACID DERIVATIVES | HOFFMAN-LA ROCHE INC. (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124688-A1 | Process for synthesizing d-tocotrienols from 2-vinylchromane compound | FDFT1, DHCR7, DDT | CYP3A4 176/4885TSHR 2099/4885PTGS1 1731/4885 |
| US-20050124687-A1 | Process for synthesizing d-tocotrienols | UGT8, DDOST, GGPS1 | CYP3A4 168/4885TSHR 1217/4885PTGS1 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.