Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.53 |
| ▸ | TTPA | P49638 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675007 | 0.87 | CYP3A4 (0.63) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL5674832 | 0.87 | CYP3A4 (0.63) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL6028036 | 0.87 | CYP3A4 (0.63) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| Ethane SCHEMBL4283975 | 0.86 | CYP3A4 (0.62) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL9096916 | 0.84 | CYP3A4 (0.56) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL7986272 | 0.84 | PTGS1 (0.56) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL9094963 | 0.84 | CYP3A4 (0.56) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL9816262 | 0.83 | PTGS1 (0.54) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL7489357 | 0.82 | CYP3A4 (0.60) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL7057336 | 0.82 | MAPT (0.57) | CYP3A4TSHRPTGS1PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |