Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.53 |
| ▸ | TTPA | P49638 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6028036 | 0.99 | CYP3A4 (0.63) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL5675007 | 0.99 | CYP3A4 (0.63) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL5674832 | 0.99 | CYP3A4 (0.63) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL9655733 | 0.86 | CYP3A4 (0.58) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL3090662 | 0.85 | ALOX5 (0.70) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL13156991 | 0.85 | ALOX5 (0.70) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL13566290 | 0.85 | ALOX5 (0.70) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL11707684 | 0.84 | ALOX5 (0.51) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL11706911 | 0.84 | ALOX5 (0.51) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL8600719 | 0.84 | PTGS1 (0.51) | CYP3A4TSHRPTGS1PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615650-B2 | Process for producing chroman compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2009-11-10 | — | — | US | disclosed |
| US-20070179304-A1 | Process for producing chroman compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-08-02 | — | — | US | disclosed |
| EP-1710239-A1 | PROCESS FOR PRODUCING CHROMAN COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179304-A1 | Process for producing chroman compound | TAF9, TAF1, CHD1 | CYP3A4 106/4885TSHR 2396/4885PTGS1 509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.